5JAX
PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue 6J7 A 401 |
| Chain | Residue |
| A | LEU296 |
| A | THR317 |
| A | ALA318 |
| A | TYR351 |
| A | HOH530 |
| A | HOH550 |
| A | HOH569 |
| A | ARG297 |
| A | LEU299 |
| A | PHE305 |
| A | GLY306 |
| A | GLU307 |
| A | LYS308 |
| A | ALA309 |
| A | ARG316 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | GLY342 |
| A | ASP344 |
| A | HOH516 |
| A | HOH573 |
| A | HOH606 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | LYS232 |
| A | ARG269 |
| A | ASP271 |
| A | ASP314 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 404 |
| Chain | Residue |
| A | LYS308 |
| A | GLN311 |
| A | GLU313 |
| A | HOH533 |
| A | HOH578 |
| A | HOH591 |
Functional Information from PROSITE/UniProt
| site_id | PS00888 |
| Number of Residues | 17 |
| Details | CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrQGArGDtFFIIskG |
| Chain | Residue | Details |
| A | ILE263-GLY279 |
| site_id | PS00889 |
| Number of Residues | 18 |
| Details | CNMP_BINDING_2 Cyclic nucleotide-binding domain signature 2. FGEkALqgedv......RTAnViA |
| Chain | Residue | Details |
| A | PHE305-ALA322 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24239458","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25271401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4KU7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QXK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
