5J8K

Architecture of supercomplex I-III2

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AA	0005739	cellular_component	mitochondrion
AA	0005743	cellular_component	mitochondrial inner membrane
AA	0005750	cellular_component	mitochondrial respiratory chain complex III
AA	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AA	0031625	molecular_function	ubiquitin protein ligase binding
AA	0046872	molecular_function	metal ion binding
AB	0004222	molecular_function	metalloendopeptidase activity
AB	0006508	biological_process	proteolysis
AB	0046872	molecular_function	metal ion binding
AC	0005739	cellular_component	mitochondrion
AC	0005743	cellular_component	mitochondrial inner membrane
AC	0005750	cellular_component	mitochondrial respiratory chain complex III
AC	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AC	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AC	0009055	molecular_function	electron transfer activity
AC	0016020	cellular_component	membrane
AC	0016491	molecular_function	oxidoreductase activity
AC	0022904	biological_process	respiratory electron transport chain
AC	0045275	cellular_component	respiratory chain complex III
AC	0046872	molecular_function	metal ion binding
AC	0070469	cellular_component	respirasome
AC	1902600	biological_process	proton transmembrane transport
AD	0009055	molecular_function	electron transfer activity
AD	0020037	molecular_function	heme binding
AE	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AE	0016020	cellular_component	membrane
AE	0051537	molecular_function	2 iron, 2 sulfur cluster binding
AF	0005739	cellular_component	mitochondrion
AF	0005743	cellular_component	mitochondrial inner membrane
AF	0005750	cellular_component	mitochondrial respiratory chain complex III
AF	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AF	0070469	cellular_component	respirasome
AG	0005739	cellular_component	mitochondrion
AG	0005743	cellular_component	mitochondrial inner membrane
AG	0005750	cellular_component	mitochondrial respiratory chain complex III
AG	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AG	0070469	cellular_component	respirasome
AH	0005750	cellular_component	mitochondrial respiratory chain complex III
AH	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AI	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AJ	0005750	cellular_component	mitochondrial respiratory chain complex III
AJ	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AK	0005750	cellular_component	mitochondrial respiratory chain complex III
AK	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AL	0005739	cellular_component	mitochondrion
AL	0005743	cellular_component	mitochondrial inner membrane
AL	0005750	cellular_component	mitochondrial respiratory chain complex III
AL	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AL	0031625	molecular_function	ubiquitin protein ligase binding
AL	0046872	molecular_function	metal ion binding
AM	0004222	molecular_function	metalloendopeptidase activity
AM	0006508	biological_process	proteolysis
AM	0046872	molecular_function	metal ion binding
AN	0005739	cellular_component	mitochondrion
AN	0005743	cellular_component	mitochondrial inner membrane
AN	0005750	cellular_component	mitochondrial respiratory chain complex III
AN	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AN	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AN	0009055	molecular_function	electron transfer activity
AN	0016020	cellular_component	membrane
AN	0016491	molecular_function	oxidoreductase activity
AN	0022904	biological_process	respiratory electron transport chain
AN	0045275	cellular_component	respiratory chain complex III
AN	0046872	molecular_function	metal ion binding
AN	0070469	cellular_component	respirasome
AN	1902600	biological_process	proton transmembrane transport
AO	0009055	molecular_function	electron transfer activity
AO	0020037	molecular_function	heme binding
AP	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AP	0016020	cellular_component	membrane
AP	0051537	molecular_function	2 iron, 2 sulfur cluster binding
AQ	0005739	cellular_component	mitochondrion
AQ	0005743	cellular_component	mitochondrial inner membrane
AQ	0005750	cellular_component	mitochondrial respiratory chain complex III
AQ	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AQ	0070469	cellular_component	respirasome
AR	0005739	cellular_component	mitochondrion
AR	0005743	cellular_component	mitochondrial inner membrane
AR	0005750	cellular_component	mitochondrial respiratory chain complex III
AR	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AR	0070469	cellular_component	respirasome
AS	0005750	cellular_component	mitochondrial respiratory chain complex III
AS	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AT	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AU	0005750	cellular_component	mitochondrial respiratory chain complex III
AU	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AV	0005750	cellular_component	mitochondrial respiratory chain complex III
AV	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryenfnnlGtSHLLRLAsSlTT

Chain	Residue	Details
AB	GLY54-THR77

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	322
Details	TRANSMEM: Helical => ECO:0000250|UniProtKB:P00157

Chain	Residue	Details
AC	PHE33-MET53
AN	TRP77-VAL98
AN	TRP113-LEU133
AN	PHE178-LEU198
AN	ILE226-THR246
AN	LEU288-HIS308
AN	ILE320-GLY340
AN	TYR347-PRO367
AC	TRP77-VAL98
AC	TRP113-LEU133
AC	PHE178-LEU198
AC	ILE226-THR246
AC	LEU288-HIS308
AC	ILE320-GLY340
AC	TYR347-PRO367
AN	PHE33-MET53

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: axial binding residue => ECO:0000250|UniProtKB:P00157

Chain	Residue	Details
AC	HIS83
AC	HIS97
AC	HIS182
AC	HIS196
AN	HIS83
AN	HIS97
AN	HIS182
AN	HIS196

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P00157

Chain	Residue	Details
AC	HIS201
AN	HIS201

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