5J47

The X-ray structure of Inhibitor Bound to JCV Helicase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005524	molecular_function	ATP binding
A	0006260	biological_process	DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 701

Chain	Residue
A	CYS303
A	CYS306
A	HIS314
A	HIS318

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site_id	AC2
Number of Residues	7
Details	binding site for residue MES A 702

Chain	Residue
A	MET610
A	HOH906
A	ILE581
A	TRP582
A	LYS601
A	ASP605
A	SER609

---

site_id	AC3
Number of Residues	11
Details	binding site for residue 6JJ A 703

Chain	Residue
A	TRP394
A	LYS419
A	ASP430
A	THR435
A	PRO550
A	LYS551
A	LEU554
A	ARG555
A	LEU558
A	LEU565
A	HOH921

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	92
Details	ZN_FING: T-ag D1-type => ECO:0000255|PROSITE-ProRule:PRU00671

Chain	Residue	Details
A	THR266-ARG358

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00671

Chain	Residue	Details
A	CYS303
A	CYS306
A	HIS314
A	HIS318

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00551

Chain	Residue	Details
A	GLY427

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