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5J1S

TorsinA-LULL1 complex, H. sapiens, bound to VHH-BS2

Functional Information from GO Data
ChainGOidnamespacecontents
A0000338biological_processprotein deneddylation
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005635cellular_componentnuclear envelope
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005788cellular_componentendoplasmic reticulum lumen
A0005789cellular_componentendoplasmic reticulum membrane
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0006979biological_processresponse to oxidative stress
A0006996biological_processorganelle organization
A0006998biological_processnuclear envelope organization
A0007155biological_processcell adhesion
A0008021cellular_componentsynaptic vesicle
A0008092molecular_functioncytoskeletal protein binding
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0019894molecular_functionkinesin binding
A0030141cellular_componentsecretory granule
A0030426cellular_componentgrowth cone
A0030659cellular_componentcytoplasmic vesicle membrane
A0031175biological_processneuron projection development
A0031410cellular_componentcytoplasmic vesicle
A0031965cellular_componentnuclear membrane
A0034504biological_processprotein localization to nucleus
A0036503biological_processERAD pathway
A0042802molecular_functionidentical protein binding
A0042995cellular_componentcell projection
A0043231cellular_componentintracellular membrane-bounded organelle
A0044319biological_processwound healing, spreading of cells
A0045104biological_processintermediate filament cytoskeleton organization
A0045202cellular_componentsynapse
A0048489biological_processsynaptic vesicle transport
A0048499biological_processsynaptic vesicle membrane organization
A0051082molecular_functionunfolded protein binding
A0051085biological_processchaperone cofactor-dependent protein refolding
A0051584biological_processregulation of dopamine uptake involved in synaptic transmission
A0051787molecular_functionmisfolded protein binding
A0061077biological_processchaperone-mediated protein folding
A0070062cellular_componentextracellular exosome
A0071763biological_processnuclear membrane organization
A0140662molecular_functionATP-dependent protein folding chaperone
A1900244biological_processpositive regulation of synaptic vesicle endocytosis
A2000008biological_processregulation of protein localization to cell surface
B0001671molecular_functionATPase activator activity
Functional Information from PDB Data
site_idAC1
Number of Residues25
Detailsbinding site for residue ATP A 401
ChainResidue
AASN68
APHE110
AGLN171
AASN208
ACYS280
ACYS319
ALYS320
AMG402
AHOH546
AHOH547
AHOH562
ALEU69
AHOH578
AHOH612
AHOH641
AHOH649
BHIS384
BARG449
APHE70
ATHR104
AGLY105
ATHR106
AGLY107
ALYS108
AASN109

site_idAC2
Number of Residues5
Detailsbinding site for residue MG A 402
ChainResidue
AASN109
AATP401
AHOH546
AHOH547
AHOH562

site_idAC3
Number of Residues3
Detailsbinding site for residue CL A 403
ChainResidue
AASN143
ATYR147
CASN33

site_idAC4
Number of Residues7
Detailsbinding site for residue MES A 404
ChainResidue
AASP64
AASN68
APHE110
ALYS113
AILE114
AGLU117
AHOH580

site_idAC5
Number of Residues5
Detailsbinding site for residue MG B 501
ChainResidue
BTHR320
BGLN323
BVAL325
BHOH613
BHOH757

site_idAC6
Number of Residues5
Detailsbinding site for residue MG C 201
ChainResidue
BTHR342
BHOH800
CTHR58
CHOH362
CHOH373

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues234
DetailsTOPO_DOM: Lumenal => ECO:0000255
ChainResidueDetails
BASN236-PHE470

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BASN286
AASN158

222415

PDB entries from 2024-07-10

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