5J0Z

Crystal structure of GLIC in complex with DHA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005886	cellular_component	plasma membrane
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CL A 401

Chain	Residue
A	PHE78
A	ARG85
E	HOH502

---

site_id	AC2
Number of Residues	2
Details	binding site for residue LMT A 402

Chain	Residue
B	LMT401
D	LMT403

---

site_id	AC3
Number of Residues	4
Details	binding site for residue LMT A 403

Chain	Residue
A	ALA237
A	LEU241
A	LMT404
E	ALA237

---

site_id	AC4
Number of Residues	3
Details	binding site for residue LMT A 404

Chain	Residue
A	ALA237
A	LMT403
B	ALA237

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 A 405

Chain	Residue
A	LYS38
A	ASN83
A	ARG109

---

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 A 406

Chain	Residue
A	ARG109
E	SER29

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ACT A 407

Chain	Residue
A	ARG77
A	ILE131
A	GLU181
E	PHE42

---

site_id	AC8
Number of Residues	1
Details	binding site for residue HXA A 408

Chain	Residue
A	ARG118

---

site_id	AC9
Number of Residues	7
Details	binding site for residue PLC A 409

Chain	Residue
A	PHE121
A	TYR194
A	ILE202
A	LEU203
A	TYR254
A	ASN307
A	PHE315

---

site_id	AD1
Number of Residues	5
Details	binding site for residue LMT B 401

Chain	Residue
A	LMT402
B	ALA237
C	ILE236
C	ALA237
D	LMT402

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 B 402

Chain	Residue
A	SER29
A	LYS38
B	ARG109

---

site_id	AD3
Number of Residues	2
Details	binding site for residue SO4 B 403

Chain	Residue
B	SER29
C	ARG109

---

site_id	AD4
Number of Residues	1
Details	binding site for residue HXA B 404

Chain	Residue
B	ARG118

---

site_id	AD5
Number of Residues	2
Details	binding site for residue SO4 C 401

Chain	Residue
C	SER29
D	ARG109

---

site_id	AD6
Number of Residues	1
Details	binding site for residue HXA C 402

Chain	Residue
C	ARG118

---

site_id	AD7
Number of Residues	2
Details	binding site for residue CL D 401

Chain	Residue
D	PHE78
D	ARG85

---

site_id	AD8
Number of Residues	3
Details	binding site for residue LMT D 402

Chain	Residue
B	LMT401
D	ALA237
E	ILE240

---

site_id	AD9
Number of Residues	3
Details	binding site for residue LMT D 403

Chain	Residue
A	LMT402
D	ALA237
E	ALA237

---

site_id	AE1
Number of Residues	1
Details	binding site for residue CL E 401

Chain	Residue
E	PHE78

---

site_id	AE2
Number of Residues	2
Details	binding site for residue SO4 E 402

Chain	Residue
D	SER29
E	ARG109

---

site_id	AE3
Number of Residues	5
Details	binding site for residue ACT E 403

Chain	Residue
D	PHE42
D	ARG105
E	ARG77
E	ILE131
E	GLU181

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	370
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	35
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---