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5IXD

Structure of human JAK1 FERM/SH2 in complex with IFN lambda receptor

Functional Information from GO Data
ChainGOidnamespacecontents
A0004715molecular_functionnon-membrane spanning protein tyrosine kinase activity
A0005524molecular_functionATP binding
A0006468biological_processprotein phosphorylation
A0016020cellular_componentmembrane
A0035556biological_processintracellular signal transduction
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue CIT A 601
ChainResidue
ALYS218
AARG230
AARG230
ALEU234
AARG237
AMET238
AASN241

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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