5ITI
A cynobacterial PP2C (tPphA) structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004722 | molecular_function | protein serine/threonine phosphatase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0032873 | biological_process | negative regulation of stress-activated MAPK cascade |
| A | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
| A | 0043124 | biological_process | negative regulation of canonical NF-kappaB signal transduction |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0090263 | biological_process | positive regulation of canonical Wnt signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | ASP34 |
| A | ASP193 |
| A | ASP231 |
| A | CA302 |
| A | HOH416 |
| A | HOH418 |
| A | HOH420 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 302 |
| Chain | Residue |
| A | CA301 |
| A | HOH407 |
| A | HOH416 |
| A | HOH443 |
| A | HOH474 |
| A | ASP34 |
| A | GLY35 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 303 |
| Chain | Residue |
| A | ASP119 |
| A | ASP193 |
| A | HOH427 |
| A | HOH437 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 304 |
| Chain | Residue |
| A | GLU198 |
| A | HIS227 |
| A | HOH445 |
| A | HOH455 |
| A | HOH487 |
