5IT1
Streptomyces peucetius CYP105P2 complex with biphenyl compound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| A | 0020037 | molecular_function | heme binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| B | 0020037 | molecular_function | heme binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| C | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| C | 0020037 | molecular_function | heme binding |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| D | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| D | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue HEM A 401 |
| Chain | Residue |
| A | LEU87 |
| A | ALA288 |
| A | ARG290 |
| A | ALA340 |
| A | PHE341 |
| A | GLY342 |
| A | HIS346 |
| A | CYS348 |
| A | ILE349 |
| A | LEU353 |
| A | GLU357 |
| A | LEU88 |
| A | HOH561 |
| A | HIS95 |
| A | ARG99 |
| A | THR233 |
| A | ALA237 |
| A | ALA238 |
| A | THR241 |
| A | THR242 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue 2OH A 402 |
| Chain | Residue |
| A | PRO82 |
| A | TRP89 |
| A | GLN177 |
| A | ALA181 |
| A | GLY186 |
| A | MET187 |
| A | ASN229 |
| A | THR233 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue HEM B 401 |
| Chain | Residue |
| B | LEU88 |
| B | HIS95 |
| B | ARG99 |
| B | PHE106 |
| B | ALA237 |
| B | ALA238 |
| B | THR241 |
| B | THR242 |
| B | ALA288 |
| B | ARG290 |
| B | ALA340 |
| B | PHE341 |
| B | GLY342 |
| B | HIS346 |
| B | CYS348 |
| B | ILE349 |
| B | HOH516 |
| B | HOH558 |
| B | HOH632 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue 2OH B 402 |
| Chain | Residue |
| B | PRO82 |
| B | TRP89 |
| B | GLN177 |
| B | ALA181 |
| B | GLY186 |
| B | MET187 |
| B | ASN229 |
| B | THR233 |
| C | 2OH402 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | binding site for residue HEM C 401 |
| Chain | Residue |
| C | LEU88 |
| C | HIS95 |
| C | ARG99 |
| C | THR233 |
| C | ALA237 |
| C | ALA238 |
| C | THR241 |
| C | THR242 |
| C | ALA288 |
| C | ARG290 |
| C | ALA340 |
| C | PHE341 |
| C | HIS346 |
| C | CYS348 |
| C | ILE349 |
| C | LEU353 |
| C | HOH525 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue 2OH C 402 |
| Chain | Residue |
| B | MET187 |
| B | 2OH402 |
| C | PRO82 |
| C | GLN177 |
| C | ALA181 |
| C | GLY186 |
| C | LEU189 |
| C | ASN229 |
| C | THR233 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue HEM D 401 |
| Chain | Residue |
| D | HOH530 |
| D | LEU88 |
| D | HIS95 |
| D | ARG99 |
| D | PHE106 |
| D | THR233 |
| D | ALA237 |
| D | ALA238 |
| D | THR241 |
| D | THR242 |
| D | ALA288 |
| D | ARG290 |
| D | ALA340 |
| D | PHE341 |
| D | GLY342 |
| D | HIS346 |
| D | CYS348 |
| D | ILE349 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue 2OH D 402 |
| Chain | Residue |
| D | PRO82 |
| D | GLN177 |
| D | ALA181 |
| D | GLY186 |
| D | MET187 |
| D | MET187 |
| D | ASN229 |
| D | THR233 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGfGAHQCIG |
| Chain | Residue | Details |
| A | PHE341-GLY350 |
