5IT1
Streptomyces peucetius CYP105P2 complex with biphenyl compound
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0004497 | molecular_function | monooxygenase activity |
B | 0005506 | molecular_function | iron ion binding |
B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
B | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
B | 0020037 | molecular_function | heme binding |
B | 0046872 | molecular_function | metal ion binding |
C | 0004497 | molecular_function | monooxygenase activity |
C | 0005506 | molecular_function | iron ion binding |
C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
C | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
C | 0020037 | molecular_function | heme binding |
C | 0046872 | molecular_function | metal ion binding |
D | 0004497 | molecular_function | monooxygenase activity |
D | 0005506 | molecular_function | iron ion binding |
D | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
D | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
D | 0020037 | molecular_function | heme binding |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 20 |
Details | binding site for residue HEM A 401 |
Chain | Residue |
A | LEU87 |
A | ALA288 |
A | ARG290 |
A | ALA340 |
A | PHE341 |
A | GLY342 |
A | HIS346 |
A | CYS348 |
A | ILE349 |
A | LEU353 |
A | GLU357 |
A | LEU88 |
A | HOH561 |
A | HIS95 |
A | ARG99 |
A | THR233 |
A | ALA237 |
A | ALA238 |
A | THR241 |
A | THR242 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue 2OH A 402 |
Chain | Residue |
A | PRO82 |
A | TRP89 |
A | GLN177 |
A | ALA181 |
A | GLY186 |
A | MET187 |
A | ASN229 |
A | THR233 |
site_id | AC3 |
Number of Residues | 19 |
Details | binding site for residue HEM B 401 |
Chain | Residue |
B | LEU88 |
B | HIS95 |
B | ARG99 |
B | PHE106 |
B | ALA237 |
B | ALA238 |
B | THR241 |
B | THR242 |
B | ALA288 |
B | ARG290 |
B | ALA340 |
B | PHE341 |
B | GLY342 |
B | HIS346 |
B | CYS348 |
B | ILE349 |
B | HOH516 |
B | HOH558 |
B | HOH632 |
site_id | AC4 |
Number of Residues | 9 |
Details | binding site for residue 2OH B 402 |
Chain | Residue |
B | PRO82 |
B | TRP89 |
B | GLN177 |
B | ALA181 |
B | GLY186 |
B | MET187 |
B | ASN229 |
B | THR233 |
C | 2OH402 |
site_id | AC5 |
Number of Residues | 17 |
Details | binding site for residue HEM C 401 |
Chain | Residue |
C | LEU88 |
C | HIS95 |
C | ARG99 |
C | THR233 |
C | ALA237 |
C | ALA238 |
C | THR241 |
C | THR242 |
C | ALA288 |
C | ARG290 |
C | ALA340 |
C | PHE341 |
C | HIS346 |
C | CYS348 |
C | ILE349 |
C | LEU353 |
C | HOH525 |
site_id | AC6 |
Number of Residues | 9 |
Details | binding site for residue 2OH C 402 |
Chain | Residue |
B | MET187 |
B | 2OH402 |
C | PRO82 |
C | GLN177 |
C | ALA181 |
C | GLY186 |
C | LEU189 |
C | ASN229 |
C | THR233 |
site_id | AC7 |
Number of Residues | 18 |
Details | binding site for residue HEM D 401 |
Chain | Residue |
D | HOH530 |
D | LEU88 |
D | HIS95 |
D | ARG99 |
D | PHE106 |
D | THR233 |
D | ALA237 |
D | ALA238 |
D | THR241 |
D | THR242 |
D | ALA288 |
D | ARG290 |
D | ALA340 |
D | PHE341 |
D | GLY342 |
D | HIS346 |
D | CYS348 |
D | ILE349 |
site_id | AC8 |
Number of Residues | 8 |
Details | binding site for residue 2OH D 402 |
Chain | Residue |
D | PRO82 |
D | GLN177 |
D | ALA181 |
D | GLY186 |
D | MET187 |
D | MET187 |
D | ASN229 |
D | THR233 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGfGAHQCIG |
Chain | Residue | Details |
A | PHE341-GLY350 |