5IRN
Crystal structure of rabbit NOD2 in an ADP-bound state (Crystal form1)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue ADP A 1101 |
| Chain | Residue |
| A | ILE231 |
| A | THR287 |
| A | PHE427 |
| A | TYR435 |
| A | PRO466 |
| A | VAL467 |
| A | TRP470 |
| A | HIS583 |
| A | HOH1211 |
| A | HOH1237 |
| A | TYR232 |
| A | THR233 |
| A | GLU280 |
| A | GLY282 |
| A | SER283 |
| A | GLY284 |
| A | LYS285 |
| A | SER286 |
Functional Information from PROSITE/UniProt
| site_id | PS00430 |
| Number of Residues | 90 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. gpefeaaackkymsklrtivaaqsrflstydgaenlclediytentlevrtevgmagplhkspaalgleelfspnghlneda.................................DTVLVVGE |
| Chain | Residue | Details |
| A | GLY191-GLU280 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 136 |
| Details | Domain: {"description":"NACHT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00136","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | Repeat: {"description":"LRR 1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 23 |
| Details | Repeat: {"description":"LRR 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 21 |
| Details | Repeat: {"description":"LRR 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | Repeat: {"description":"LRR 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | Repeat: {"description":"LRR 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 21 |
| Details | Repeat: {"description":"LRR 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | Repeat: {"description":"LRR 7","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | Repeat: {"description":"LRR 8","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Repeat: {"description":"LRR 9","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27283905","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IRM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IRN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00136","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27283905","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IRN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 1 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"UniProtKB","id":"Q9HC29","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
