5IPA
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with (E)-3-(furan-3-yl)-1-(pyrrolidin-1-yl)prop-2-en-1-one at 1.78A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue 6C8 A 301 |
| Chain | Residue |
| A | PHE114 |
| A | TRP138 |
| A | GLU180 |
| A | LEU183 |
| A | 6C8302 |
| A | 6C8303 |
| A | HOH410 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue 6C8 A 302 |
| Chain | Residue |
| A | PHE110 |
| A | MET142 |
| A | THR149 |
| A | ASN176 |
| A | ASN179 |
| A | TRP207 |
| A | 6C8301 |
| A | 6C8303 |
| A | GLY106 |
| A | ILE107 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue 6C8 A 303 |
| Chain | Residue |
| A | ILE107 |
| A | PHE110 |
| A | TRP138 |
| A | MET142 |
| A | TRP145 |
| A | THR149 |
| A | ASN176 |
| A | ASN179 |
| A | GLU180 |
| A | TRP207 |
| A | 6C8301 |
| A | 6C8302 |
