5ILQ

Crystal structure of truncated unliganded Aspartate Transcarbamoylase from Plasmodium falciparum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004070	molecular_function	aspartate carbamoyltransferase activity
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006520	biological_process	amino acid metabolic process
A	0016020	cellular_component	membrane
A	0016597	molecular_function	amino acid binding
A	0016740	molecular_function	transferase activity
A	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
A	0044205	biological_process	'de novo' UMP biosynthetic process
B	0004070	molecular_function	aspartate carbamoyltransferase activity
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006520	biological_process	amino acid metabolic process
B	0016020	cellular_component	membrane
B	0016597	molecular_function	amino acid binding
B	0016740	molecular_function	transferase activity
B	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
B	0044205	biological_process	'de novo' UMP biosynthetic process
C	0004070	molecular_function	aspartate carbamoyltransferase activity
C	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
C	0006221	biological_process	pyrimidine nucleotide biosynthetic process
C	0006520	biological_process	amino acid metabolic process
C	0016020	cellular_component	membrane
C	0016597	molecular_function	amino acid binding
C	0016740	molecular_function	transferase activity
C	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
C	0044205	biological_process	'de novo' UMP biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL A 401

Chain	Residue
A	ASN57
A	SER59
A	VAL170
A	SER173
A	SER174
A	LYS175

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site_id	AC2
Number of Residues	2
Details	binding site for residue GOL A 402

Chain	Residue
A	ASP67
A	ASP68

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site_id	AC3
Number of Residues	8
Details	binding site for residue GOL B 401

Chain	Residue
B	LYS124
B	VAL125
B	HOH501
C	VAL125
C	SO4401
C	HOH503
C	HOH506
A	VAL125

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site_id	AC4
Number of Residues	9
Details	binding site for residue SO4 C 401

Chain	Residue
A	LEU119
A	LYS124
B	LEU119
B	LYS124
B	GOL401
C	LEU119
C	LYS124
C	HOH503
C	HOH506

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Functional Information from PROSITE/UniProt

site_id	PS00097
Number of Residues	8
Details	CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FlEpSTRT

Chain	Residue	Details
A	PHE103-THR110

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site_id	PS00181
Number of Residues	17
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPIinag.NGTGeHptqS

Chain	Residue	Details
A	LYS175-SER191

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