5ILQ
Crystal structure of truncated unliganded Aspartate Transcarbamoylase from Plasmodium falciparum
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| C | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| C | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | ASN57 |
| A | SER59 |
| A | VAL170 |
| A | SER173 |
| A | SER174 |
| A | LYS175 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ASP67 |
| A | ASP68 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | LYS124 |
| B | VAL125 |
| B | HOH501 |
| C | VAL125 |
| C | SO4401 |
| C | HOH503 |
| C | HOH506 |
| A | VAL125 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 C 401 |
| Chain | Residue |
| A | LEU119 |
| A | LYS124 |
| B | LEU119 |
| B | LYS124 |
| B | GOL401 |
| C | LEU119 |
| C | LYS124 |
| C | HOH503 |
| C | HOH506 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FlEpSTRT |
| Chain | Residue | Details |
| A | PHE103-THR110 |
| site_id | PS00181 |
| Number of Residues | 17 |
| Details | GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPIinag.NGTGeHptqS |
| Chain | Residue | Details |
| A | LYS175-SER191 |
