5ILO
Crystal structure of photoreceptor dehydrogenase from Drosophila melanogaster
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004745 | molecular_function | all-trans-retinol dehydrogenase (NAD+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0042572 | biological_process | retinol metabolic process |
| A | 0042574 | biological_process | retinal metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004745 | molecular_function | all-trans-retinol dehydrogenase (NAD+) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0042572 | biological_process | retinol metabolic process |
| B | 0042574 | biological_process | retinal metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue NAD A 301 |
| Chain | Residue |
| A | GLY12 |
| A | VAL90 |
| A | ALA91 |
| A | GLY92 |
| A | ILE93 |
| A | ARG101 |
| A | VAL105 |
| A | MET135 |
| A | SER137 |
| A | TYR150 |
| A | LYS154 |
| A | GLY15 |
| A | PRO182 |
| A | GLY183 |
| A | THR187 |
| A | MET189 |
| A | HOH414 |
| A | HOH416 |
| A | GLY16 |
| A | ILE17 |
| A | ASP37 |
| A | LEU38 |
| A | MET62 |
| A | ASP63 |
| A | VAL64 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue NAD B 301 |
| Chain | Residue |
| B | GLY12 |
| B | GLY15 |
| B | GLY16 |
| B | ILE17 |
| B | ASP37 |
| B | LEU38 |
| B | MET62 |
| B | ASP63 |
| B | VAL64 |
| B | VAL90 |
| B | GLY92 |
| B | ILE93 |
| B | VAL105 |
| B | MET135 |
| B | SER136 |
| B | SER137 |
| B | TYR150 |
| B | LYS154 |
| B | GLY183 |
| B | THR185 |
| B | THR187 |
| B | HOH406 |
| B | HOH422 |
| B | HOH453 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvvgldpmfiIpvYGATKAGIiNFTrCLA |
| Chain | Residue | Details |
| A | SER137-ALA165 |
