5IJE

Crystal structure of Equine Serum Albumin in the presence of 30 mM zinc at pH 7.4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005504	molecular_function	fatty acid binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0008289	molecular_function	lipid binding
A	0009267	biological_process	cellular response to starvation
A	0015643	molecular_function	toxic substance binding
A	0019825	molecular_function	oxygen binding
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031667	biological_process	response to nutrient levels
A	0032991	cellular_component	protein-containing complex
A	0046872	molecular_function	metal ion binding
A	0051902	biological_process	negative regulation of mitochondrial depolarization
A	0072732	biological_process	cellular response to calcium ion starvation
A	1903981	molecular_function	enterobactin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 601

Chain	Residue
A	HIS3
A	GLU6
A	HIS9
A	HOH773
A	HOH831

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 602

Chain	Residue
A	HIS18
A	HOH777
A	HOH860
A	HOH897

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 603

Chain	Residue
A	HIS67
A	ASP248
A	HOH703
A	HOH731

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 604

Chain	Residue
A	HIS145
A	HOH830
A	HOH840
A	HOH889

---

site_id	AC5
Number of Residues	5
Details	binding site for residue ZN A 605

Chain	Residue
A	LEU237
A	HIS241
A	HOH766
A	HOH829
A	HOH881

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN A 606

Chain	Residue
A	HIS246
A	HOH854
A	HOH877
A	HOH900

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN A 607

Chain	Residue
A	GLU152
A	HIS156
A	HIS287
A	HOH826

---

site_id	AC8
Number of Residues	3
Details	binding site for residue ZN A 608

Chain	Residue
A	ASP311
A	HIS317
A	HOH740

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN A 609

Chain	Residue
A	HIS451
A	HOH864
A	HOH867
A	HOH892

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN A 610

Chain	Residue
A	GLU517
A	HOH728
A	HOH814
A	HOH857

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN A 611

Chain	Residue
A	ASP511
A	HOH707
A	HOH797
A	HOH862

---

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN A 612

Chain	Residue
A	CYS34
A	ALA78
A	HOH816
A	HOH945

---

site_id	AD4
Number of Residues	3
Details	binding site for residue ZN A 613

Chain	Residue
A	GLU128
A	GLU441
A	ARG444

---

site_id	AD5
Number of Residues	4
Details	binding site for residue SO4 A 614

Chain	Residue
A	ALA303
A	LEU304
A	ALA305
A	ARG336

---

Functional Information from PROSITE/UniProt

site_id	PS00212
Number of Residues	25
Details	ALBUMIN_1 Albumin domain signature. YkadfteCCpaDdklaCLipkldaL

Chain	Residue	Details
A	TYR160-LEU184
A	TYR352-PHE376
A	PHE550-LEU574

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	192
Details	Domain: {"description":"Albumin 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	197
Details	Domain: {"description":"Albumin 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P02770","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P02769","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28567254","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IIH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02770","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P07724","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---