5IGQ

WD40 domain of Human E3 Ubiquitin Ligase COP1 (RFWD2) bound to peptide from Trib1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0061630	molecular_function	ubiquitin protein ligase activity
B	0061630	molecular_function	ubiquitin protein ligase activity
C	0061630	molecular_function	ubiquitin protein ligase activity
D	0061630	molecular_function	ubiquitin protein ligase activity
E	0061630	molecular_function	ubiquitin protein ligase activity
F	0061630	molecular_function	ubiquitin protein ligase activity

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IVSAstDsQLKLWNV

Chain	Residue	Details
A	ILE613-VAL627

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	Repeat: {"description":"WD 2"}

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site_id	SWS_FT_FI2
Number of Residues	240
Details	Repeat: {"description":"WD 3"}

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site_id	SWS_FT_FI3
Number of Residues	240
Details	Repeat: {"description":"WD 4"}

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site_id	SWS_FT_FI4
Number of Residues	228
Details	Repeat: {"description":"WD 5"}

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site_id	SWS_FT_FI5
Number of Residues	234
Details	Repeat: {"description":"WD 6"}

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site_id	SWS_FT_FI6
Number of Residues	12
Details	Region: {"description":"Interaction with TRIB1","evidences":[{"source":"PubMed","id":"27041596","evidenceCode":"ECO:0000269"}]}

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site_id	SWS_FT_FI7
Number of Residues	12
Details	Site: {"description":"Interaction with TRIB1","evidences":[{"source":"PubMed","id":"27041596","evidenceCode":"ECO:0000269"}]}

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site_id	SWS_FT_FI8
Number of Residues	30
Details	Motif: {"description":"COP1-binding","evidences":[{"source":"UniProtKB","id":"Q8K4K4","evidenceCode":"ECO:0000250"}]}

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