5IFM

Human NONO (p54nrb) Homodimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
E	0003676	molecular_function	nucleic acid binding
E	0003723	molecular_function	RNA binding
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
G	0003676	molecular_function	nucleic acid binding
G	0003723	molecular_function	RNA binding
H	0003676	molecular_function	nucleic acid binding
H	0003723	molecular_function	RNA binding
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
J	0003676	molecular_function	nucleic acid binding
J	0003723	molecular_function	RNA binding
K	0003676	molecular_function	nucleic acid binding
K	0003723	molecular_function	RNA binding
L	0003676	molecular_function	nucleic acid binding
L	0003723	molecular_function	RNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 401

Chain	Residue
A	ARG140
E	GLN245

---

site_id	AC2
Number of Residues	6
Details	binding site for residue PRO A 402

Chain	Residue
A	PRO156
A	GLN157
A	PHE218
A	ARG220
B	GLU250
D	ARG202

---

site_id	AC3
Number of Residues	1
Details	binding site for residue K A 403

Chain	Residue
A	GLU166

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL B 401

Chain	Residue
B	GLU102
B	ARG115
D	GLU53
D	GLY54

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL B 402

Chain	Residue
B	GLU165
B	SER169
B	GLY172
B	GLN173
B	VAL174

---

site_id	AC6
Number of Residues	1
Details	binding site for residue K B 403

Chain	Residue
B	GLU166

---

site_id	AC7
Number of Residues	2
Details	binding site for residue CL C 401

Chain	Residue
C	ARG140
G	GLN245

---

site_id	AC8
Number of Residues	3
Details	binding site for residue CL C 402

Chain	Residue
C	ASN244
C	GLN245
G	ARG140

---

site_id	AC9
Number of Residues	3
Details	binding site for residue PRO C 403

Chain	Residue
B	ARG202
C	GLN157
C	ARG220

---

site_id	AD1
Number of Residues	9
Details	binding site for residue GOL C 404

Chain	Residue
C	GLN173
C	SER196
C	GLY197
C	PRO199
C	ALA200
C	LYS203
G	GLU87
G	ARG91
G	VAL103

---

site_id	AD2
Number of Residues	6
Details	binding site for residue GOL C 405

Chain	Residue
C	ASN61
C	PHE62
C	GLU67
C	THR118
D	VAL127
D	GLU128

---

site_id	AD3
Number of Residues	1
Details	binding site for residue K C 406

Chain	Residue
C	GLU166

---

site_id	AD4
Number of Residues	3
Details	binding site for residue CL D 401

Chain	Residue
D	ARG140
D	ARG142
D	GLU234

---

site_id	AD5
Number of Residues	5
Details	binding site for residue GOL D 402

Chain	Residue
C	LEU163
C	LEU215
D	ARG251
D	GLN253
D	PRO254

---

site_id	AD6
Number of Residues	2
Details	binding site for residue K D 403

Chain	Residue
C	ARG251
D	GLU166

---

site_id	AD7
Number of Residues	2
Details	binding site for residue CL E 401

Chain	Residue
A	GLN245
E	ARG140

---

site_id	AD8
Number of Residues	2
Details	binding site for residue CL F 401

Chain	Residue
F	ARG140
I	GLN245

---

site_id	AD9
Number of Residues	2
Details	binding site for residue CL F 402

Chain	Residue
F	GLN245
I	ARG140

---

site_id	AE1
Number of Residues	2
Details	binding site for residue CL G 401

Chain	Residue
G	LYS126
G	GLU234

---

site_id	AE2
Number of Residues	2
Details	binding site for residue CL H 401

Chain	Residue
H	GLN245
K	ARG140

---

site_id	AE3
Number of Residues	2
Details	binding site for residue CL L 401

Chain	Residue
L	ARG75
L	SER147

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
A	SER147
J	SER147
K	SER147
L	SER147
B	SER147
C	SER147
D	SER147
E	SER147
F	SER147
G	SER147
H	SER147
I	SER147

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS198
J	LYS198
K	LYS198
L	LYS198
B	LYS198
C	LYS198
D	LYS198
E	LYS198
F	LYS198
G	LYS198
H	LYS198
I	LYS198

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER262
J	SER262
K	SER262
L	SER262
B	SER262
C	SER262
D	SER262
E	SER262
F	SER262
G	SER262
H	SER262
I	SER262

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q99K48

Chain	Residue	Details
A	LYS295
J	LYS295
K	LYS295
L	LYS295
B	LYS295
C	LYS295
D	LYS295
E	LYS295
F	LYS295
G	LYS295
H	LYS295
I	LYS295

---

site_id	SWS_FT_FI5
Number of Residues	96
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS60
B	LYS96
B	LYS99
B	LYS126
B	LYS190
B	LYS243
B	LYS249
C	LYS60
C	LYS96
C	LYS99
C	LYS126
C	LYS190
C	LYS243
C	LYS249
D	LYS60
D	LYS96
D	LYS99
D	LYS126
A	LYS96
D	LYS190
D	LYS243
D	LYS249
E	LYS60
E	LYS96
E	LYS99
E	LYS126
E	LYS190
E	LYS243
A	LYS99
E	LYS249
F	LYS60
F	LYS96
F	LYS99
F	LYS126
F	LYS190
F	LYS243
F	LYS249
G	LYS60
A	LYS126
G	LYS96
G	LYS99
G	LYS126
G	LYS190
G	LYS243
G	LYS249
H	LYS60
H	LYS96
A	LYS190
H	LYS99
H	LYS126
H	LYS190
H	LYS243
H	LYS249
I	LYS60
I	LYS96
I	LYS99
I	LYS126
A	LYS243
I	LYS190
I	LYS243
I	LYS249
J	LYS60
J	LYS96
J	LYS99
J	LYS126
J	LYS190
J	LYS243
A	LYS249
J	LYS249
K	LYS60
K	LYS96
K	LYS99
K	LYS126
K	LYS190
K	LYS243
K	LYS249
L	LYS60
B	LYS60
L	LYS96
L	LYS99
L	LYS126
L	LYS190
L	LYS243
L	LYS249

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS198
J	LYS198
K	LYS198
L	LYS198
B	LYS198
C	LYS198
D	LYS198
E	LYS198
F	LYS198
G	LYS198
H	LYS198
I	LYS198

---