5IFM

Human NONO (p54nrb) Homodimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
E	0003676	molecular_function	nucleic acid binding
E	0003723	molecular_function	RNA binding
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
G	0003676	molecular_function	nucleic acid binding
G	0003723	molecular_function	RNA binding
H	0003676	molecular_function	nucleic acid binding
H	0003723	molecular_function	RNA binding
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
J	0003676	molecular_function	nucleic acid binding
J	0003723	molecular_function	RNA binding
K	0003676	molecular_function	nucleic acid binding
K	0003723	molecular_function	RNA binding
L	0003676	molecular_function	nucleic acid binding
L	0003723	molecular_function	RNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 401

Chain	Residue
A	ARG140
E	GLN245

---

site_id	AC2
Number of Residues	6
Details	binding site for residue PRO A 402

Chain	Residue
A	PRO156
A	GLN157
A	PHE218
A	ARG220
B	GLU250
D	ARG202

---

site_id	AC3
Number of Residues	1
Details	binding site for residue K A 403

Chain	Residue
A	GLU166

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL B 401

Chain	Residue
B	GLU102
B	ARG115
D	GLU53
D	GLY54

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL B 402

Chain	Residue
B	GLU165
B	SER169
B	GLY172
B	GLN173
B	VAL174

---

site_id	AC6
Number of Residues	1
Details	binding site for residue K B 403

Chain	Residue
B	GLU166

---

site_id	AC7
Number of Residues	2
Details	binding site for residue CL C 401

Chain	Residue
C	ARG140
G	GLN245

---

site_id	AC8
Number of Residues	3
Details	binding site for residue CL C 402

Chain	Residue
C	ASN244
C	GLN245
G	ARG140

---

site_id	AC9
Number of Residues	3
Details	binding site for residue PRO C 403

Chain	Residue
B	ARG202
C	GLN157
C	ARG220

---

site_id	AD1
Number of Residues	9
Details	binding site for residue GOL C 404

Chain	Residue
C	GLN173
C	SER196
C	GLY197
C	PRO199
C	ALA200
C	LYS203
G	GLU87
G	ARG91
G	VAL103

---

site_id	AD2
Number of Residues	6
Details	binding site for residue GOL C 405

Chain	Residue
C	ASN61
C	PHE62
C	GLU67
C	THR118
D	VAL127
D	GLU128

---

site_id	AD3
Number of Residues	1
Details	binding site for residue K C 406

Chain	Residue
C	GLU166

---

site_id	AD4
Number of Residues	3
Details	binding site for residue CL D 401

Chain	Residue
D	ARG140
D	ARG142
D	GLU234

---

site_id	AD5
Number of Residues	5
Details	binding site for residue GOL D 402

Chain	Residue
C	LEU163
C	LEU215
D	ARG251
D	GLN253
D	PRO254

---

site_id	AD6
Number of Residues	2
Details	binding site for residue K D 403

Chain	Residue
C	ARG251
D	GLU166

---

site_id	AD7
Number of Residues	2
Details	binding site for residue CL E 401

Chain	Residue
A	GLN245
E	ARG140

---

site_id	AD8
Number of Residues	2
Details	binding site for residue CL F 401

Chain	Residue
F	ARG140
I	GLN245

---

site_id	AD9
Number of Residues	2
Details	binding site for residue CL F 402

Chain	Residue
F	GLN245
I	ARG140

---

site_id	AE1
Number of Residues	2
Details	binding site for residue CL G 401

Chain	Residue
G	LYS126
G	GLU234

---

site_id	AE2
Number of Residues	2
Details	binding site for residue CL H 401

Chain	Residue
H	GLN245
K	ARG140

---

site_id	AE3
Number of Residues	2
Details	binding site for residue CL L 401

Chain	Residue
L	ARG75
L	SER147

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	804
Details	Domain: {"description":"RRM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	972
Details	Domain: {"description":"RRM 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q99K48","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	96
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---