5IFK

Purine nucleoside phosphorylase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004731	molecular_function	purine-nucleoside phosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0009116	biological_process	nucleoside metabolic process
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
B	0003824	molecular_function	catalytic activity
B	0004731	molecular_function	purine-nucleoside phosphorylase activity
B	0005737	cellular_component	cytoplasm
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0009116	biological_process	nucleoside metabolic process
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
C	0003824	molecular_function	catalytic activity
C	0004731	molecular_function	purine-nucleoside phosphorylase activity
C	0005737	cellular_component	cytoplasm
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0009116	biological_process	nucleoside metabolic process
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue HPA A 401

Chain	Residue
A	ALA129
A	CYS258
A	HOH581
A	HOH629
A	ALA130
A	GLY131
A	PHE213
A	GLU214
A	VAL230
A	GLY231
A	THR255
A	ASN256

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site_id	AC2
Number of Residues	13
Details	binding site for residue HPA B 401

Chain	Residue
B	ALA129
B	ALA130
B	GLY131
B	PHE213
B	GLU214
B	VAL230
B	GLY231
B	MET232
B	THR255
B	ASN256
B	CYS258
B	HOH593
B	HOH637

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site_id	AC3
Number of Residues	12
Details	binding site for residue HPA C 401

Chain	Residue
C	ALA129
C	ALA130
C	GLY131
C	PHE213
C	GLU214
C	VAL230
C	GLY231
C	MET232
C	THR255
C	ASN256
C	HOH596
C	HOH599

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Functional Information from PROSITE/UniProt

site_id	PS01240
Number of Residues	43
Details	PNP_MTAP_2 Purine and other phosphorylases family 2 signature. VlmnGrlHsYeghsLaetVhpIrAlhllGsinvLIvtNAaGGI

Chain	Residue	Details
A	VAL91-ILE133

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