5IF8

Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue 6AX A 801

Chain	Residue
A	ARG312
A	TRP317
A	LYS318
A	GLU319
A	LEU342
A	GLN346
A	GLU349

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site_id	AC2
Number of Residues	6
Details	binding site for residue DMS A 802

Chain	Residue
A	LEU469
A	ILE504
A	PHE520
A	THR570
A	LYS281
A	ASN466

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site_id	AC3
Number of Residues	3
Details	binding site for residue EDO A 804

Chain	Residue
A	ARG279
A	LYS539
A	ARG566

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site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 805

Chain	Residue
A	LYS289
A	ASP419
A	SER420
A	ARG454

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