Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
| B | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
| B | 0016592 | cellular_component | mediator complex |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0045023 | biological_process | G0 to G1 transition |
| B | 0045746 | biological_process | negative regulation of Notch signaling pathway |
| B | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| B | 1990508 | cellular_component | CKM complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 69Z A 401 |
| Chain | Residue |
| A | VAL27 |
| A | LEU158 |
| A | ASP173 |
| A | ARG356 |
| A | EDO404 |
| A | TYR32 |
| A | VAL35 |
| A | ALA50 |
| A | LYS52 |
| A | PHE97 |
| A | ASP98 |
| A | ALA100 |
| A | ASN156 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | HIS106 |
| A | LYS355 |
| A | ARG356 |
| A | GLU357 |
| A | HOH520 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | ARG71 |
| A | LYS83 |
| A | VAL84 |
| A | HOH515 |
| B | ASP147 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | GLU66 |
| A | LEU70 |
| A | ILE79 |
| A | PHE97 |
| A | ALA172 |
| A | ASP173 |
| A | PHE176 |
| A | 69Z401 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue FMT A 405 |
| Chain | Residue |
| A | ARG71 |
| A | GLU72 |
| A | HOH524 |
| B | GLN7 |
| B | SER9 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 406 |
| Chain | Residue |
| A | LYS8 |
| A | PRO262 |
| A | ASP264 |
| A | HIS276 |
| A | MET280 |
| A | ARG285 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue FMT A 407 |
| Chain | Residue |
| A | GLU17 |
| A | PHE20 |
| A | GLU21 |
| A | TYR22 |
| A | GLU23 |
| A | LYS41 |
| A | HOH610 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 301 |
| Chain | Residue |
| B | ALA0 |
| B | ALA2 |
| B | ARG157 |
| B | HOH419 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue FMT B 302 |
| Chain | Residue |
| B | GLN41 |
| B | FMT303 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue FMT B 303 |
| Chain | Residue |
| B | GLN41 |
| B | THR45 |
| B | THR66 |
| B | PHE69 |
| B | LYS70 |
| B | FMT302 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue FMT B 304 |
| Chain | Residue |
| B | HIS203 |
| B | LYS211 |
| B | ALA213 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 305 |
| Chain | Residue |
| B | PHE5 |
| B | PRO194 |
| B | PHE195 |
| B | HOH454 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue FMT B 306 |
| Chain | Residue |
| B | GLN49 |
| B | GLN59 |
| B | ALA63 |
| B | TYR156 |
| B | TYR184 |
| B | ARG185 |
| B | HOH406 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 26 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGRGTYGHVYkAkrkdgkddkd........YALK |
| Chain | Residue | Details |
| A | VAL27-LYS52 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpaNILV |
| Chain | Residue | Details |
| A | VAL147-VAL159 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Region: {"description":"Interaction with CCNC"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 98 |
| Details | Domain: {"description":"Cyclin N-terminal"} |
