5I8S

Structure of Mouse Acireductone dioxygenase with Ni2+ ion and pentanoic acid in the active site

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006555	biological_process	methionine metabolic process
A	0008652	biological_process	amino acid biosynthetic process
A	0009086	biological_process	methionine biosynthetic process
A	0010308	molecular_function	acireductone dioxygenase (Ni2+-requiring) activity
A	0010309	molecular_function	acireductone dioxygenase [iron(II)-requiring] activity
A	0016020	cellular_component	membrane
A	0016151	molecular_function	nickel cation binding
A	0016491	molecular_function	oxidoreductase activity
A	0019509	biological_process	L-methionine salvage from methylthioadenosine
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue NI A 201

Chain	Residue
A	HIS88
A	HIS90
A	GLU94
A	HIS133
A	HOH311
A	HOH323

---

site_id	AC2
Number of Residues	8
Details	binding site for residue LEA A 202

Chain	Residue
A	PHE135
A	ALA145
A	HOH311
A	HOH323
A	HOH336
A	ILE69
A	PHE84
A	ARG96

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16783794, ECO:0000269|PubMed:26858196, ECO:0007744|PDB:1VR3, ECO:0007744|PDB:5I8S, ECO:0007744|PDB:5I8T, ECO:0007744|PDB:5I91, ECO:0007744|PDB:5I93

Chain	Residue	Details
A	HIS88
A	HIS90
A	GLU94
A	HIS133

---