Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004802 | molecular_function | transketolase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005829 | cellular_component | cytosol |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0006163 | biological_process | purine nucleotide metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue TPP A 701 |
| Chain | Residue |
| A | ALA30 |
| A | ILE187 |
| A | SER188 |
| A | ILE189 |
| A | ILE248 |
| A | CYS261 |
| A | ASP379 |
| A | GLU415 |
| A | PHE442 |
| A | TYR445 |
| A | HIS478 |
| A | CYS66 |
| A | 5SP702 |
| A | CA703 |
| A | HOH843 |
| A | HOH998 |
| A | HOH1043 |
| A | HOH1234 |
| A | GLY114 |
| A | PRO115 |
| A | LEU116 |
| A | ASP155 |
| A | GLY156 |
| A | GLU160 |
| A | ASN185 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 5SP A 702 |
| Chain | Residue |
| A | HIS27 |
| A | CYS66 |
| A | HIS100 |
| A | ILE189 |
| A | ARG356 |
| A | SER383 |
| A | PHE439 |
| A | HIS466 |
| A | ASP474 |
| A | HIS478 |
| A | ARG525 |
| A | TPP701 |
| A | HOH801 |
| A | HOH1142 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 703 |
| Chain | Residue |
| A | ASP155 |
| A | ASN185 |
| A | ILE187 |
| A | TPP701 |
| A | HOH998 |
Functional Information from PROSITE/UniProt
| site_id | PS00801 |
| Number of Residues | 21 |
| Details | TRANSKETOLASE_1 Transketolase signature 1. RllaVDavaaanSGHPGapLG |
| Chain | Residue | Details |
| A | ARG13-GLY33 | |
| site_id | PS00802 |
| Number of Residues | 17 |
| Details | TRANSKETOLASE_2 Transketolase signature 2. GEDGPTHqPIEtlAhfR |
| Chain | Residue | Details |
| A | GLY472-ARG488 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU415 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS27 | |
| A | SER383 | |
| A | GLU415 | |
| A | PHE442 | |
| A | HIS466 | |
| A | ASP474 | |
| A | ARG525 | |
| A | CYS66 | |
| A | GLY114 | |
| A | ASP155 | |
| A | GLY156 | |
| A | ASN185 | |
| A | ILE187 | |
| A | CYS261 | |
| A | ARG356 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Important for catalytic activity => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS27 | |
| A | CYS261 | |
