5I4R

Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (trypsin-modified)

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
D	0003746	molecular_function	translation elongation factor activity
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
D	0006414	biological_process	translational elongation
G	0003924	molecular_function	GTPase activity
G	0005525	molecular_function	GTP binding
H	0003746	molecular_function	translation elongation factor activity
H	0003924	molecular_function	GTPase activity
H	0005525	molecular_function	GTP binding
H	0006414	biological_process	translational elongation

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue GDP C 101

Chain	Residue
C	ASP22
D	SER174
D	ALA175
D	LEU176
C	GLY24
C	LYS25
C	THR26
C	THR27
D	ASN136
D	LYS137
D	ASP139
D	MET140

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site_id	AC2
Number of Residues	13
Details	binding site for residue GDP G 101

Chain	Residue
G	ASP22
G	HIS23
G	GLY24
G	LYS25
G	THR26
G	THR27
H	ASN136
H	LYS137
H	ASP139
H	MET140
H	SER174
H	ALA175
H	LEU176

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
D	ASP81
D	ASN136
H	ASP81
H	ASN136

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842

Chain	Residue	Details
D	LYS314
H	LYS314

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:19150849, ECO:0000269|PubMed:24141193, ECO:0000269|PubMed:8416965

Chain	Residue	Details
D	THR383
H	THR383

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	1
Details	M-CSA 535

Chain	Residue	Details
D	HIS85	electrostatic stabiliser

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site_id	MCSA2
Number of Residues	1
Details	M-CSA 535

Chain	Residue	Details
H	HIS85	electrostatic stabiliser

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