Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 29 |
Details | binding site for residue ATP A 1000 |
Chain | Residue |
A | GLY554 |
A | VAL629 |
A | SER633 |
A | ASN673 |
A | LYS677 |
A | ASN678 |
A | LEU680 |
A | MG1001 |
A | HOH1101 |
A | HOH1122 |
A | HOH1133 |
A | THR555 |
A | HOH1143 |
A | HOH1151 |
A | HOH1152 |
A | HOH1153 |
A | HOH1164 |
A | HOH1179 |
A | HOH1192 |
A | HOH1200 |
A | HOH1208 |
A | HOH1245 |
A | THR557 |
A | ILE559 |
A | LEU579 |
A | LYS581 |
A | GLN626 |
A | GLU627 |
A | PHE628 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue MG A 1001 |
Chain | Residue |
A | ASN678 |
A | ATP1000 |
A | HOH1151 |
A | HOH1192 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue GOL A 1002 |
Chain | Residue |
A | ARG715 |
A | TRP718 |
A | LYS752 |
A | HOH1103 |
A | HOH1121 |
A | HOH1131 |
A | HOH1179 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | SITE: Breakpoint for translocation to form PCM1-JAK2 fusion protein |
Chain | Residue | Details |
A | ASP710 | |
Chain | Residue | Details |
A | TYR570 | |