5I4I

Crystal Structure of Transketolase from Pichia Stipitis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004802	molecular_function	transketolase activity
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0006098	biological_process	pentose-phosphate shunt

Functional Information from PROSITE/UniProt

site_id	PS00801
Number of Residues	21
Details	TRANSKETOLASE_1 Transketolase signature 1. RllaVDavaaanSGHPGapLG

Chain	Residue	Details
A	ARG13-GLY33

---

site_id	PS00802
Number of Residues	17
Details	TRANSKETOLASE_2 Transketolase signature 2. GEDGPTHqPIEtlAhfR

Chain	Residue	Details
A	GLY472-ARG488

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30155962","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5I5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XQK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29243887","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30155962","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HYV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XPS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XQA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XRV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XU2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29243887","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30155962","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HYV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XPS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XQA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XS6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30155962","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XPS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XQA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XRV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29243887","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30155962","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HYV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XPS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XQA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XRV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XU2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30155962","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5I51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XRV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30155962","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XPS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XRV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29243887","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30155962","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5I51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XRV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XS6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HYV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XPS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XQA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5I51","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Site: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"27578891","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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