5HRE

The crystal structure of AsfvPolX:DNA3 binary complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006259	biological_process	DNA metabolic process
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0006303	biological_process	double-strand break repair via nonhomologous end joining
A	0009059	biological_process	macromolecule biosynthetic process
A	0016779	molecular_function	nucleotidyltransferase activity
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding
A	0071897	biological_process	DNA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MN A 201

Chain	Residue
A	ASP49
A	ASP51
A	FMT202
A	HOH306
A	HOH320
B	DT9

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site_id	AC2
Number of Residues	8
Details	binding site for residue FMT A 202

Chain	Residue
A	ASP51
A	MN201
A	HOH306
A	HOH345
B	DT9
A	GLY38
A	SER39
A	ARG42

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site_id	AC3
Number of Residues	2
Details	binding site for residue PO4 A 203

Chain	Residue
A	ARG41
A	HOH307

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site_id	AC4
Number of Residues	4
Details	binding site for residue PO4 A 204

Chain	Residue
A	ILE113
A	THR155
A	GLU156
A	HOH381

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Functional Information from PROSITE/UniProt

site_id	PS00522
Number of Residues	20
Details	DNA_POLYMERASE_X DNA polymerase family X signature. GSLrREekmLnDVDLLIivP

Chain	Residue	Details
A	GLY38-PRO57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:11685239, ECO:0000305|PubMed:28245220

Chain	Residue	Details
A	ASP49
A	ASP51
A	ASP100

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Stabilizes dGTP in a syn confromation to overcome the Watson-Crick base pairing constraint => ECO:0000269|PubMed:24617852

Chain	Residue	Details
A	HIS115

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