5HOX

X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. Synchrotron data set. (LVFFAEDCGSNKCAII(SAR)LMV).

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
B	0016020	cellular_component	membrane
C	0016020	cellular_component	membrane
D	0016020	cellular_component	membrane
E	0016020	cellular_component	membrane
F	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue JEF F 101

Chain	Residue
A	PHE4
C	PHE4
D	PHE4

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	SITE: Cleavage; by alpha-secretase => ECO:0000305|PubMed:11851430

Chain	Residue	Details
A	ORN1
B	ORN1
C	ORN1
D	ORN1
E	ORN1
F	ORN1

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site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Cleavage; by theta-secretase => ECO:0000269|PubMed:16816112

Chain	Residue	Details
A	PHE4
B	PHE4
C	PHE4
D	PHE4
E	PHE4
F	PHE4

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site_id	SWS_FT_FI3
Number of Residues	6
Details	SITE: Implicated in free radical propagation => ECO:0000250

Chain	Residue	Details
A	SAR18
B	SAR18
C	SAR18
D	SAR18
E	SAR18
F	SAR18

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site_id	SWS_FT_FI4
Number of Residues	6
Details	SITE: Susceptible to oxidation => ECO:0000269|PubMed:10535332

Chain	Residue	Details
A	MET20
B	MET20
C	MET20
D	MET20
E	MET20
F	MET20

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