5HMI
HDM2 in complex with a 3,3-Disubstituted Piperidine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 62T A 1001 |
| Chain | Residue |
| A | GLN24 |
| A | HIS96 |
| A | ILE99 |
| A | TYR100 |
| A | HOH1136 |
| A | HOH1137 |
| B | LYS51 |
| B | TYR55 |
| B | 62T1001 |
| B | HOH1115 |
| A | LEU54 |
| A | GLY58 |
| A | ILE61 |
| A | MET62 |
| A | TYR67 |
| A | GLN72 |
| A | PHE91 |
| A | VAL93 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 1002 |
| Chain | Residue |
| A | GLU95 |
| A | HIS96 |
| A | ARG97 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue 62T B 1001 |
| Chain | Residue |
| A | LYS51 |
| A | 62T1001 |
| B | LEU54 |
| B | GLY58 |
| B | ILE61 |
| B | TYR67 |
| B | GLN72 |
| B | PHE91 |
| B | VAL93 |
| B | HIS96 |
| B | ILE99 |
| B | TYR100 |
| B | HOH1102 |
| B | HOH1108 |
| B | HOH1115 |
| B | HOH1125 |
