5HJD
AF9 YEATS in complex with histone H3 Crotonylation at K18
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
| K | 0006355 | biological_process | regulation of DNA-templated transcription |
| N | 0006355 | biological_process | regulation of DNA-templated transcription |
| Q | 0006355 | biological_process | regulation of DNA-templated transcription |
| T | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CU A 201 |
| Chain | Residue |
| A | PHE105 |
| A | HIS107 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | ARG99 |
| A | PHE100 |
| A | ASP101 |
| A | ARG118 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CU C 201 |
| Chain | Residue |
| C | HIS41 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CU C 202 |
| Chain | Residue |
| C | HIS116 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 C 203 |
| Chain | Residue |
| C | HIS41 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 201 |
| Chain | Residue |
| E | PHE100 |
| E | ASP101 |
| E | ARG118 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 G 201 |
| Chain | Residue |
| G | ARG16 |
| G | PHE35 |
| G | ARG37 |
| G | LYS72 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 G 202 |
| Chain | Residue |
| G | TYR88 |
| G | LYS97 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 G 203 |
| Chain | Residue |
| E | ALA2 |
| G | LYS10 |
| G | PRO39 |
| G | GLU40 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 G 204 |
| Chain | Residue |
| G | HIS116 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 G 205 |
| Chain | Residue |
| G | ARG20 |
| G | THR24 |
| G | VAL25 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue CU K 201 |
| Chain | Residue |
| K | HIS107 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 K 202 |
| Chain | Residue |
| K | PHE35 |
| K | ARG37 |
| K | LYS72 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 N 201 |
| Chain | Residue |
| N | HIS107 |
| N | ASN115 |
| N | HIS116 |
| Q | ARG16 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 N 202 |
| Chain | Residue |
| N | LYS121 |
| Q | LYS121 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 Q 201 |
| Chain | Residue |
| Q | PHE100 |
| Q | ASP101 |
| Q | ARG118 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 T 201 |
| Chain | Residue |
| T | THR24 |
| T | VAL25 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 T 202 |
| Chain | Residue |
| T | PHE35 |
| T | ARG37 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 959 |
| Details | Domain: {"description":"YEATS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00376","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Region: {"description":"Histone H3K9cr binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30385749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Site: {"description":"Histone H3K9cr binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30385749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Citrulline; alternate","evidences":[{"source":"PubMed","id":"15345777","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16497732","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16567635","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
