5HH3

OxyA from Actinoplanes teichomyceticus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0016491	molecular_function	oxidoreductase activity
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0017000	biological_process	antibiotic biosynthetic process
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
C	0004497	molecular_function	monooxygenase activity
C	0005506	molecular_function	iron ion binding
C	0005515	molecular_function	protein binding
C	0016491	molecular_function	oxidoreductase activity
C	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
C	0017000	biological_process	antibiotic biosynthetic process
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue HEM A 401

Chain	Residue
A	LEU85
A	THR282
A	HIS283
A	ARG285
A	LEU308
A	ALA334
A	PHE335
A	GLY336
A	ILE339
A	HIS340
A	CYS342
A	THR86
A	GLY344
A	LEU347
A	HOH535
A	HOH549
C	GLY-5
A	HIS93
A	ARG97
A	PHE228
A	ALA232
A	GLY233
A	GLN236
A	THR278

---

site_id	AC2
Number of Residues	3
Details	binding site for residue GOL A 402

Chain	Residue
A	ARG97
A	ALA101
A	HIS341

---

site_id	AC3
Number of Residues	7
Details	binding site for residue GOL A 403

Chain	Residue
A	ARG274
A	ASN312
A	ARG314
A	ASN315
A	GLU320
A	ASP321
A	ARG327

---

site_id	AC4
Number of Residues	5
Details	binding site for residue ACT A 404

Chain	Residue
A	PHE104
A	CYS342
A	LEU343
A	ARG345
A	SER346

---

site_id	AC5
Number of Residues	22
Details	binding site for residue HEM C 401

Chain	Residue
C	LEU85
C	THR86
C	HIS93
C	ARG97
C	PHE228
C	GLY233
C	GLN236
C	VAL237
C	THR278
C	THR282
C	HIS283
C	ARG285
C	LEU308
C	ALA334
C	PHE335
C	GLY336
C	ILE339
C	HIS340
C	CYS342
C	GLY344
C	HOH559
C	HOH566

---

site_id	AC6
Number of Residues	6
Details	binding site for residue GOL C 402

Chain	Residue
A	ARG174
C	GLY44
C	ARG95
C	ARG98
C	MET99
C	HOH626

---

site_id	AC7
Number of Residues	5
Details	binding site for residue GOL C 403

Chain	Residue
C	GLY131
C	GLY132
C	ASP390
C	TRP391
C	HOH584

---

site_id	AC8
Number of Residues	6
Details	binding site for residue GOL C 404

Chain	Residue
C	ASP270
C	GLU331
C	HIS332
C	ARG345
C	HOH533
C	HOH552

---

site_id	AC9
Number of Residues	8
Details	binding site for residue GOL C 405

Chain	Residue
C	THR0
C	MET1
C	PHE2
C	GLU3
C	GLU4
C	ARG46
C	HOH536
C	HOH538

---

site_id	AD1
Number of Residues	2
Details	binding site for residue GOL C 406

Chain	Residue
A	ARG46
C	GLU12

---

site_id	AD2
Number of Residues	6
Details	binding site for residue GOL C 407

Chain	Residue
C	ARG18
C	LEU247
C	ASP250
C	ASP251
C	TYR275
C	HOH558

---

site_id	AD3
Number of Residues	6
Details	binding site for residue GOL C 408

Chain	Residue
C	HOH511
C	ARG314
C	ASN315
C	GLU320
C	ARG327
C	GLU331

---

site_id	AD4
Number of Residues	4
Details	binding site for residue ACT C 409

Chain	Residue
C	ALA232
C	ASP235
C	GLN236
C	ARG239

---

site_id	AD5
Number of Residues	2
Details	binding site for residue ACT C 410

Chain	Residue
C	GLU128
C	ARG362

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Functional Information from PROSITE/UniProt

site_id	PS00086
Number of Residues	10
Details	CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGIHHCLG

Chain	Residue	Details
A	PHE335-GLY344

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