5HH1
Crystal structure of human Naa60 mutant - F34A in complex with CoA
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue COA A 201 |
| Chain | Residue |
| A | TRP33 |
| A | GLY113 |
| A | SER114 |
| A | ASN143 |
| A | THR145 |
| A | PHE149 |
| A | ASN152 |
| A | ARG153 |
| A | HOH302 |
| A | HOH313 |
| A | HOH322 |
| A | SER100 |
| A | HOH351 |
| A | HOH364 |
| A | HOH379 |
| A | HOH410 |
| A | HOH442 |
| A | LEU101 |
| A | GLY102 |
| A | VAL103 |
| A | ARG108 |
| A | LYS109 |
| A | HIS110 |
| A | GLY111 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 169 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | Region: {"description":"Required for homodimerization","evidences":[{"source":"PubMed","id":"27320834","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"27320834","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27550639","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27320834","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ICV","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"5ICW","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27320834","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27550639","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HGZ","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"5HH0","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"5HH1","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"5ICV","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"5ICW","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Required to position thioacetyl group","evidences":[{"source":"PubMed","id":"27550639","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-acetyllysine; by autocatalysis","evidences":[{"source":"PubMed","id":"21981917","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine; by autocatalysis","evidences":[{"source":"PubMed","id":"21981917","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
