5HGQ
Loa loa Lysyl-tRNA synthetase in complex with Cladosporin.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004824 | molecular_function | lysine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004824 | molecular_function | lysine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| C | 0004824 | molecular_function | lysine-tRNA ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| C | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| D | 0004824 | molecular_function | lysine-tRNA ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| D | 0006430 | biological_process | lysyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue LYS A 601 |
| Chain | Residue |
| A | ALA210 |
| A | ARG255 |
| A | GLU271 |
| A | ASN430 |
| A | TYR432 |
| A | GLY479 |
| A | TRP480 |
| A | KRS602 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue KRS A 602 |
| Chain | Residue |
| A | THR262 |
| A | HIS263 |
| A | ASN264 |
| A | PHE267 |
| A | GLU427 |
| A | ILE428 |
| A | GLY483 |
| A | ARG486 |
| A | LYS601 |
| A | GLU257 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue GOL D 601 |
| Chain | Residue |
| D | GLU386 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue LYS D 602 |
| Chain | Residue |
| D | ALA231 |
| D | GLU233 |
| D | ARG255 |
| D | TYR273 |
| D | ASN430 |
| D | TYR432 |
| D | GLU434 |
| D | GLY479 |
| D | TRP480 |
| D | KRS603 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue KRS D 603 |
| Chain | Residue |
| D | ARG255 |
| D | GLU257 |
| D | THR262 |
| D | HIS263 |
| D | ASN264 |
| D | PHE267 |
| D | SER269 |
| D | GLU427 |
| D | ILE428 |
| D | VAL429 |
| D | ASN430 |
| D | GLY483 |
| D | ARG486 |
| D | LYS602 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue LYS B 601 |
| Chain | Residue |
| B | GLY209 |
| B | ALA210 |
| B | ARG255 |
| B | GLU271 |
| B | TYR273 |
| B | ASN430 |
| B | TYR432 |
| B | GLY479 |
| B | KRS602 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue KRS B 602 |
| Chain | Residue |
| B | ARG255 |
| B | GLU257 |
| B | THR262 |
| B | HIS263 |
| B | ASN264 |
| B | SER269 |
| B | ASN430 |
| B | GLY483 |
| B | ARG486 |
| B | ILE497 |
| B | LYS601 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue LYS C 601 |
| Chain | Residue |
| C | GLY209 |
| C | ALA210 |
| C | GLU233 |
| C | ARG255 |
| C | TYR273 |
| C | ASN430 |
| C | GLU434 |
| C | GLY479 |
| C | TRP480 |
| C | KRS602 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue KRS C 602 |
| Chain | Residue |
| C | GLU257 |
| C | THR262 |
| C | HIS263 |
| C | ASN264 |
| C | PHE267 |
| C | GLU427 |
| C | ILE428 |
| C | VAL429 |
| C | GLY483 |
| C | ARG486 |
| C | LYS601 |
