5HDR
Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004560 | molecular_function | alpha-L-fucosidase activity |
| A | 0005764 | cellular_component | lysosome |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0016139 | biological_process | glycoside catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004560 | molecular_function | alpha-L-fucosidase activity |
| B | 0005764 | cellular_component | lysosome |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006004 | biological_process | fucose metabolic process |
| B | 0016139 | biological_process | glycoside catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004560 | molecular_function | alpha-L-fucosidase activity |
| C | 0005764 | cellular_component | lysosome |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006004 | biological_process | fucose metabolic process |
| C | 0016139 | biological_process | glycoside catabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004560 | molecular_function | alpha-L-fucosidase activity |
| D | 0005764 | cellular_component | lysosome |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006004 | biological_process | fucose metabolic process |
| D | 0016139 | biological_process | glycoside catabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | TRP232 |
| A | ARG262 |
| A | ARG271 |
| A | HIS272 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | GLY83 |
| A | ASN402 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue IMD A 503 |
| Chain | Residue |
| A | PHE359 |
| A | TRP117 |
| A | MET120 |
| A | TYR168 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue H79 A 504 |
| Chain | Residue |
| A | HIS66 |
| A | GLU87 |
| A | TRP88 |
| A | HIS135 |
| A | TYR178 |
| A | ASP229 |
| A | TRP232 |
| A | GLU288 |
| A | TRP316 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 501 |
| Chain | Residue |
| B | PRO96 |
| B | ALA97 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| B | TRP232 |
| B | ARG262 |
| B | ARG271 |
| B | HIS272 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue IMD B 503 |
| Chain | Residue |
| B | ALA63 |
| B | TRP117 |
| B | MET120 |
| B | TYR168 |
| B | PHE351 |
| B | PHE359 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue H79 B 504 |
| Chain | Residue |
| B | HIS66 |
| B | GLU87 |
| B | TRP88 |
| B | HIS135 |
| B | TYR178 |
| B | ASP229 |
| B | TRP232 |
| B | GLU288 |
| B | TRP316 |
| B | HOH735 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 501 |
| Chain | Residue |
| C | TRP232 |
| C | ARG262 |
| C | ARG271 |
| C | HIS272 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue IMD C 502 |
| Chain | Residue |
| C | TRP117 |
| C | MET120 |
| C | ALA121 |
| C | TYR168 |
| C | PHE359 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue H79 C 503 |
| Chain | Residue |
| C | HIS66 |
| C | GLU87 |
| C | TRP88 |
| C | HIS135 |
| C | TYR178 |
| C | ASP229 |
| C | TRP232 |
| C | GLU288 |
| C | HOH687 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue IMD D 501 |
| Chain | Residue |
| D | TRP117 |
| D | MET120 |
| D | ALA121 |
| D | TYR168 |
| D | PHE359 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue H79 D 502 |
| Chain | Residue |
| D | HIS66 |
| D | GLU87 |
| D | TRP88 |
| D | TRP92 |
| D | HIS135 |
| D | TYR178 |
| D | ASP229 |
| D | TRP232 |
| D | GLU288 |
| D | TRP316 |
