5HCN
GPN-loop GTPase Npa3 in complex with GMPPCP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue DAO A 301 |
| Chain | Residue |
| A | ASN144 |
| A | MET154 |
| A | CYS158 |
| A | TRP186 |
| A | LEU232 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue GCP A 302 |
| Chain | Residue |
| A | LYS16 |
| A | THR17 |
| A | THR18 |
| A | GLY109 |
| A | ASN173 |
| A | LYS174 |
| A | ASP176 |
| A | SER238 |
| A | SER239 |
| A | PHE240 |
| A | MG303 |
| A | HOH401 |
| A | HOH402 |
| A | HOH404 |
| A | ALA12 |
| A | GLY13 |
| A | SER14 |
| A | GLY15 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | THR17 |
| A | GCP302 |
| A | HOH401 |
| A | HOH402 |
| A | HOH404 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | GLN21 |
| A | ARG45 |
| A | PRO47 |
| A | VAL177 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 305 |
| Chain | Residue |
| A | LYS179 |
| A | PHE182 |
| A | TRP186 |
| A | ASP189 |
| A | SER216 |
| A | LEU217 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Motif: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01416","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01416","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Motif: {"description":"Gly-Pro-Asn (GPN)-loop; involved in dimer interface","evidences":[{"source":"UniProtKB","id":"Q9UYR9","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU01416","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Motif: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01416","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Motif: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01416","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Motif: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01416","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26711263","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5HCN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26711263","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HCI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26711263","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HCI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HCN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Site: {"description":"Stabilizes the phosphate intermediate; shared with dimeric partner","evidences":[{"source":"UniProtKB","id":"Q9UYR9","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
