5HCI

GPN-loop GTPase Npa3 in complex with GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
B	0003924	molecular_function	GTPase activity
C	0003924	molecular_function	GTPase activity
D	0003924	molecular_function	GTPase activity
E	0003924	molecular_function	GTPase activity
F	0003924	molecular_function	GTPase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue GDP A 301

Chain	Residue
A	MET11
A	ASP176
A	VAL177
A	SER238
A	SER239
A	PHE240
A	MG302
A	HOH402
A	HOH403
A	HOH418
A	HOH419
A	GLY13
B	ARG143
A	SER14
A	GLY15
A	LYS16
A	THR17
A	THR18
A	ASN173
A	LYS174

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 302

Chain	Residue
A	THR17
A	GDP301
A	HOH402
A	HOH403
A	HOH410
A	HOH419

---

site_id	AC3
Number of Residues	4
Details	binding site for residue GOL A 303

Chain	Residue
A	GLN101
A	ASP253
E	LYS96
E	GOL304

---

site_id	AC4
Number of Residues	18
Details	binding site for residue GDP B 301

Chain	Residue
B	MET11
B	GLY13
B	SER14
B	GLY15
B	LYS16
B	THR17
B	THR18
B	ASN173
B	LYS174
B	ASP176
B	VAL177
B	SER238
B	SER239
B	PHE240
B	MG302
B	HOH405
B	HOH411
B	HOH415

---

site_id	AC5
Number of Residues	6
Details	binding site for residue MG B 302

Chain	Residue
B	THR17
B	GDP301
B	HOH403
B	HOH405
B	HOH409
B	HOH411

---

site_id	AC6
Number of Residues	18
Details	binding site for residue GDP C 301

Chain	Residue
C	GLY13
C	SER14
C	GLY15
C	LYS16
C	THR17
C	THR18
C	ASN173
C	LYS174
C	ASP176
C	VAL177
C	SER238
C	SER239
C	PHE240
C	MG302
C	HOH401
C	HOH404
C	HOH405
C	HOH411

---

site_id	AC7
Number of Residues	7
Details	binding site for residue MG C 302

Chain	Residue
C	THR17
C	ASP40
C	GDP301
C	HOH401
C	HOH404
C	HOH405
C	HOH410

---

site_id	AC8
Number of Residues	5
Details	binding site for residue GOL C 303

Chain	Residue
B	GLY49
C	ASP233
C	VAL234
C	GLU247
C	CYS251

---

site_id	AC9
Number of Residues	16
Details	binding site for residue GDP D 301

Chain	Residue
D	HOH408
D	MET11
D	GLY13
D	SER14
D	GLY15
D	LYS16
D	THR17
D	THR18
D	ASN173
D	LYS174
D	ASP176
D	VAL177
D	SER238
D	SER239
D	PHE240
D	MG302

---

site_id	AD1
Number of Residues	5
Details	binding site for residue MG D 302

Chain	Residue
D	THR17
D	GDP301
D	HOH402
D	HOH406
D	HOH408

---

site_id	AD2
Number of Residues	17
Details	binding site for residue GDP E 301

Chain	Residue
E	MET11
E	GLY13
E	SER14
E	GLY15
E	LYS16
E	THR17
E	THR18
E	ASN173
E	LYS174
E	ASP176
E	VAL177
E	SER238
E	SER239
E	PHE240
E	MG302
E	HOH404
E	HOH414

---

site_id	AD3
Number of Residues	6
Details	binding site for residue MG E 302

Chain	Residue
E	THR17
E	GDP301
E	HOH402
E	HOH404
E	HOH408
E	HOH414

---

site_id	AD4
Number of Residues	6
Details	binding site for residue GOL E 303

Chain	Residue
C	TYR35
C	ASN51
C	LEU92
C	LYS96
E	ASP257
E	GLN261

---

site_id	AD5
Number of Residues	4
Details	binding site for residue GOL E 304

Chain	Residue
A	SER4
A	ASN102
A	ASP253
A	GOL303

---

site_id	AD6
Number of Residues	14
Details	binding site for residue GDP F 301

Chain	Residue
F	GLY13
F	GLY15
F	LYS16
F	THR17
F	THR18
F	ASN173
F	LYS174
F	ASP176
F	VAL177
F	SER238
F	SER239
F	PHE240
F	MG302
F	HOH405

---

site_id	AD7
Number of Residues	5
Details	binding site for residue MG F 302

Chain	Residue
F	THR17
F	GDP301
F	HOH401
F	HOH402
F	HOH405

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9UYR9

Chain	Residue	Details
A	GLY13
A	ASN173
B	GLY13
B	ASN173
C	GLY13
C	ASN173
D	GLY13
D	ASN173
E	GLY13
E	ASN173
F	GLY13
F	ASN173

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Stabilizes the phosphate intermediate; shared with dimeric partner => ECO:0000250|UniProtKB:Q9UYR9

Chain	Residue	Details
A	ASN72
B	ASN72
C	ASN72
D	ASN72
E	ASN72
F	ASN72

---