5H8J
Crystal structure of Medicago truncatula N-carbamoylputrescine amidohydrolase (MtCPA) in complex with cadaverine
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006596 | biological_process | polyamine biosynthetic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
A | 0033388 | biological_process | putrescine biosynthetic process from arginine |
A | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
B | 0006596 | biological_process | polyamine biosynthetic process |
B | 0016787 | molecular_function | hydrolase activity |
B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
B | 0033388 | biological_process | putrescine biosynthetic process from arginine |
B | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
C | 0006596 | biological_process | polyamine biosynthetic process |
C | 0016787 | molecular_function | hydrolase activity |
C | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
C | 0033388 | biological_process | putrescine biosynthetic process from arginine |
C | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
D | 0006596 | biological_process | polyamine biosynthetic process |
D | 0016787 | molecular_function | hydrolase activity |
D | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
D | 0033388 | biological_process | putrescine biosynthetic process from arginine |
D | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
E | 0006596 | biological_process | polyamine biosynthetic process |
E | 0016787 | molecular_function | hydrolase activity |
E | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
E | 0033388 | biological_process | putrescine biosynthetic process from arginine |
E | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
F | 0006596 | biological_process | polyamine biosynthetic process |
F | 0016787 | molecular_function | hydrolase activity |
F | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
F | 0033388 | biological_process | putrescine biosynthetic process from arginine |
F | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
G | 0006596 | biological_process | polyamine biosynthetic process |
G | 0016787 | molecular_function | hydrolase activity |
G | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
G | 0033388 | biological_process | putrescine biosynthetic process from arginine |
G | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
H | 0006596 | biological_process | polyamine biosynthetic process |
H | 0016787 | molecular_function | hydrolase activity |
H | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
H | 0033388 | biological_process | putrescine biosynthetic process from arginine |
H | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
I | 0006596 | biological_process | polyamine biosynthetic process |
I | 0016787 | molecular_function | hydrolase activity |
I | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
I | 0033388 | biological_process | putrescine biosynthetic process from arginine |
I | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
J | 0006596 | biological_process | polyamine biosynthetic process |
J | 0016787 | molecular_function | hydrolase activity |
J | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
J | 0033388 | biological_process | putrescine biosynthetic process from arginine |
J | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
K | 0006596 | biological_process | polyamine biosynthetic process |
K | 0016787 | molecular_function | hydrolase activity |
K | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
K | 0033388 | biological_process | putrescine biosynthetic process from arginine |
K | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
L | 0006596 | biological_process | polyamine biosynthetic process |
L | 0016787 | molecular_function | hydrolase activity |
L | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
L | 0033388 | biological_process | putrescine biosynthetic process from arginine |
L | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
M | 0006596 | biological_process | polyamine biosynthetic process |
M | 0016787 | molecular_function | hydrolase activity |
M | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
M | 0033388 | biological_process | putrescine biosynthetic process from arginine |
M | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
N | 0006596 | biological_process | polyamine biosynthetic process |
N | 0016787 | molecular_function | hydrolase activity |
N | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
N | 0033388 | biological_process | putrescine biosynthetic process from arginine |
N | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
O | 0006596 | biological_process | polyamine biosynthetic process |
O | 0016787 | molecular_function | hydrolase activity |
O | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
O | 0033388 | biological_process | putrescine biosynthetic process from arginine |
O | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
P | 0006596 | biological_process | polyamine biosynthetic process |
P | 0016787 | molecular_function | hydrolase activity |
P | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
P | 0033388 | biological_process | putrescine biosynthetic process from arginine |
P | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue GOL A 401 |
Chain | Residue |
A | ASP194 |
A | HIS198 |
B | MET273 |
B | TRP277 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue GOL A 402 |
Chain | Residue |
A | HOH635 |
B | SER195 |
B | HIS198 |
A | MET273 |
A | TRP277 |
A | HOH521 |
A | HOH535 |
A | HOH564 |
site_id | AC3 |
Number of Residues | 1 |
Details | binding site for residue PEG A 403 |
Chain | Residue |
A | HOH511 |
site_id | AC4 |
Number of Residues | 2 |
Details | binding site for residue GOL A 404 |
Chain | Residue |
A | ASN137 |
A | HOH620 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue EDO A 405 |
Chain | Residue |
A | ARG283 |
A | PRO285 |
A | ASP286 |
A | HOH524 |
A | HOH541 |
B | VAL300 |
site_id | AC6 |
Number of Residues | 9 |
Details | binding site for residue N2P B 401 |
Chain | Residue |
A | TRP277 |
A | HOH523 |
B | TYR54 |
B | TYR130 |
B | GLU132 |
B | CYS158 |
B | ALA183 |
B | GLU187 |
B | HOH538 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue GOL B 402 |
Chain | Residue |
B | ARG66 |
B | PHE95 |
B | HOH502 |
B | HOH542 |
B | HOH547 |
B | HOH570 |
site_id | AC8 |
Number of Residues | 6 |
Details | binding site for residue PGE B 403 |
Chain | Residue |
A | ASP295 |
B | ALA171 |
B | LEU172 |
B | ARG274 |
B | HOH577 |
B | HOH598 |
site_id | AC9 |
Number of Residues | 8 |
Details | binding site for residue N2P C 401 |
Chain | Residue |
C | TYR54 |
C | TYR130 |
C | GLU132 |
C | CYS158 |
C | ALA183 |
C | GLU187 |
C | HOH505 |
C | HOH529 |
site_id | AD1 |
Number of Residues | 7 |
Details | binding site for residue GOL C 402 |
Chain | Residue |
C | SER195 |
C | HIS198 |
C | HOH503 |
C | HOH555 |
C | HOH603 |
D | MET273 |
D | TRP277 |
site_id | AD2 |
Number of Residues | 4 |
Details | binding site for residue GOL C 403 |
Chain | Residue |
C | SER23 |
C | PRO74 |
C | THR75 |
C | ARG78 |
site_id | AD3 |
Number of Residues | 7 |
Details | binding site for residue GOL C 404 |
Chain | Residue |
C | VAL22 |
C | GLU51 |
C | GLY52 |
C | PHE55 |
C | ARG66 |
C | HOH515 |
C | HOH527 |
site_id | AD4 |
Number of Residues | 7 |
Details | binding site for residue EDO C 405 |
Chain | Residue |
C | ARG283 |
C | PRO285 |
C | ASP286 |
C | HOH543 |
C | HOH590 |
E | PRO138 |
F | HOH513 |
site_id | AD5 |
Number of Residues | 10 |
Details | binding site for residue N2P D 401 |
Chain | Residue |
C | TRP277 |
D | GLU48 |
D | TYR54 |
D | PRO125 |
D | GLU132 |
D | CYS158 |
D | ALA183 |
D | GLU187 |
D | HOH528 |
D | HOH593 |
site_id | AD6 |
Number of Residues | 6 |
Details | binding site for residue GOL D 402 |
Chain | Residue |
C | MET273 |
C | TRP277 |
D | HIS198 |
D | HOH549 |
D | HOH567 |
D | HOH746 |
site_id | AD7 |
Number of Residues | 2 |
Details | binding site for residue EDO D 403 |
Chain | Residue |
D | ASP112 |
D | GLY113 |
site_id | AD8 |
Number of Residues | 7 |
Details | binding site for residue N2P E 401 |
Chain | Residue |
F | HOH529 |
E | TYR54 |
E | GLU132 |
E | CYS158 |
E | ALA183 |
E | GLU187 |
E | HOH516 |
site_id | AD9 |
Number of Residues | 4 |
Details | binding site for residue GOL E 402 |
Chain | Residue |
E | MET273 |
E | TRP277 |
E | HOH529 |
F | HIS198 |
site_id | AE1 |
Number of Residues | 5 |
Details | binding site for residue GOL E 403 |
Chain | Residue |
E | VAL22 |
E | SER23 |
E | THR75 |
E | ARG78 |
E | HOH518 |
site_id | AE2 |
Number of Residues | 9 |
Details | binding site for residue GOL F 401 |
Chain | Residue |
E | SER195 |
E | HIS198 |
F | LEU211 |
F | MET273 |
F | TRP277 |
F | HOH502 |
F | HOH507 |
F | HOH558 |
F | HOH642 |
site_id | AE3 |
Number of Residues | 10 |
Details | binding site for residue N2P F 402 |
Chain | Residue |
E | TRP277 |
F | GLU48 |
F | TYR54 |
F | TYR130 |
F | GLU132 |
F | CYS158 |
F | ALA183 |
F | GLU187 |
F | HOH520 |
F | HOH543 |
site_id | AE4 |
Number of Residues | 4 |
Details | binding site for residue GOL F 403 |
Chain | Residue |
F | SER23 |
F | PRO74 |
F | THR75 |
F | ARG78 |
site_id | AE5 |
Number of Residues | 7 |
Details | binding site for residue EDO F 404 |
Chain | Residue |
C | HOH516 |
D | HOH619 |
E | VAL300 |
F | PRO285 |
F | ASP286 |
F | HOH553 |
F | HOH636 |
site_id | AE6 |
Number of Residues | 9 |
Details | binding site for residue N2P G 401 |
Chain | Residue |
G | TYR54 |
G | PRO125 |
G | GLU132 |
G | CYS158 |
G | ALA183 |
G | GLU187 |
G | HOH538 |
G | HOH549 |
H | TRP277 |
site_id | AE7 |
Number of Residues | 4 |
Details | binding site for residue PEG G 402 |
Chain | Residue |
G | ARG7 |
G | GLN147 |
G | LYS152 |
G | HOH502 |
site_id | AE8 |
Number of Residues | 5 |
Details | binding site for residue GOL G 403 |
Chain | Residue |
G | GLU257 |
G | HOH504 |
G | HOH505 |
L | LEU32 |
L | GLU258 |
site_id | AE9 |
Number of Residues | 5 |
Details | binding site for residue GOL H 401 |
Chain | Residue |
G | HIS198 |
G | HOH539 |
H | THR246 |
H | MET273 |
H | TRP277 |
site_id | AF1 |
Number of Residues | 7 |
Details | binding site for residue GOL I 401 |
Chain | Residue |
I | MET273 |
I | TRP277 |
I | HOH505 |
I | HOH507 |
I | HOH564 |
I | HOH648 |
J | HIS198 |
site_id | AF2 |
Number of Residues | 4 |
Details | binding site for residue GOL I 402 |
Chain | Residue |
I | SER23 |
I | THR75 |
I | ARG78 |
I | HOH511 |
site_id | AF3 |
Number of Residues | 6 |
Details | binding site for residue GOL I 403 |
Chain | Residue |
I | TYR54 |
I | GLN57 |
I | TYR130 |
I | ALA183 |
I | ILE184 |
I | GLY185 |
site_id | AF4 |
Number of Residues | 6 |
Details | binding site for residue EDO I 404 |
Chain | Residue |
I | PRO285 |
I | ASP286 |
I | HOH549 |
J | VAL300 |
K | HOH593 |
L | HOH512 |
site_id | AF5 |
Number of Residues | 8 |
Details | binding site for residue N2P J 401 |
Chain | Residue |
I | TRP277 |
I | HOH518 |
J | TYR54 |
J | GLU132 |
J | CYS158 |
J | ALA183 |
J | GLU187 |
J | HOH527 |
site_id | AF6 |
Number of Residues | 4 |
Details | binding site for residue EDO J 402 |
Chain | Residue |
J | ARG274 |
J | PHE280 |
J | HOH547 |
J | HOH662 |
site_id | AF7 |
Number of Residues | 9 |
Details | binding site for residue N2P K 401 |
Chain | Residue |
K | TYR54 |
K | TYR130 |
K | GLU132 |
K | CYS158 |
K | ALA183 |
K | GLU187 |
K | HOH510 |
L | TRP277 |
L | HOH526 |
site_id | AF8 |
Number of Residues | 6 |
Details | binding site for residue GOL K 402 |
Chain | Residue |
K | HIS198 |
K | HOH503 |
K | HOH585 |
K | HOH608 |
L | MET273 |
L | TRP277 |
site_id | AF9 |
Number of Residues | 5 |
Details | binding site for residue GOL K 403 |
Chain | Residue |
K | MET273 |
K | TRP277 |
K | HOH504 |
K | HOH516 |
L | HIS198 |
site_id | AG1 |
Number of Residues | 7 |
Details | binding site for residue EDO K 404 |
Chain | Residue |
K | ARG283 |
K | ASP286 |
K | HOH508 |
K | HOH569 |
K | HOH573 |
K | HOH667 |
L | VAL300 |
site_id | AG2 |
Number of Residues | 8 |
Details | binding site for residue N2P L 401 |
Chain | Residue |
K | TRP277 |
L | TYR54 |
L | GLU132 |
L | CYS158 |
L | ALA183 |
L | GLU187 |
L | HOH560 |
L | HOH596 |
site_id | AG3 |
Number of Residues | 5 |
Details | binding site for residue PEG L 402 |
Chain | Residue |
L | LYS84 |
L | ASP112 |
L | GLY113 |
L | THR114 |
L | HOH564 |
site_id | AG4 |
Number of Residues | 8 |
Details | binding site for residue EDO L 403 |
Chain | Residue |
I | HOH543 |
K | VAL300 |
L | ARG283 |
L | PRO285 |
L | ASP286 |
L | HOH528 |
L | HOH539 |
L | HOH559 |
site_id | AG5 |
Number of Residues | 8 |
Details | binding site for residue N2P M 401 |
Chain | Residue |
M | GLU48 |
M | TYR54 |
M | GLU132 |
M | CYS158 |
M | ALA183 |
M | GLU187 |
M | HOH550 |
M | HOH553 |
site_id | AG6 |
Number of Residues | 7 |
Details | binding site for residue GOL M 402 |
Chain | Residue |
M | ILE193 |
M | SER195 |
M | HIS198 |
M | HOH503 |
M | HOH504 |
M | HOH608 |
N | MET273 |
site_id | AG7 |
Number of Residues | 5 |
Details | binding site for residue GOL M 403 |
Chain | Residue |
M | MET273 |
M | TRP277 |
M | HOH515 |
M | HOH517 |
N | HIS198 |
site_id | AG8 |
Number of Residues | 5 |
Details | binding site for residue GOL M 404 |
Chain | Residue |
M | SER23 |
M | THR75 |
M | ARG78 |
M | HOH519 |
M | HOH535 |
site_id | AG9 |
Number of Residues | 9 |
Details | binding site for residue N2P N 401 |
Chain | Residue |
M | TRP277 |
N | TYR54 |
N | GLU132 |
N | CYS158 |
N | TRP159 |
N | ALA183 |
N | GLU187 |
N | HOH517 |
N | HOH575 |
site_id | AH1 |
Number of Residues | 5 |
Details | binding site for residue GOL N 402 |
Chain | Residue |
N | SER23 |
N | PRO74 |
N | THR75 |
N | ARG78 |
N | HOH616 |
site_id | AH2 |
Number of Residues | 7 |
Details | binding site for residue EDO N 403 |
Chain | Residue |
K | HOH512 |
K | HOH667 |
N | ARG283 |
N | PRO285 |
N | ASP286 |
N | HOH548 |
N | HOH669 |
site_id | AH3 |
Number of Residues | 9 |
Details | binding site for residue N2P O 401 |
Chain | Residue |
O | TYR54 |
O | GLU132 |
O | CYS158 |
O | ALA183 |
O | ILE184 |
O | GLU187 |
O | HOH537 |
O | HOH571 |
P | TRP277 |
site_id | AH4 |
Number of Residues | 6 |
Details | binding site for residue GOL O 402 |
Chain | Residue |
O | SER195 |
O | HIS198 |
O | HOH505 |
O | HOH579 |
P | TRP277 |
P | HOH416 |
site_id | AH5 |
Number of Residues | 4 |
Details | binding site for residue GOL O 403 |
Chain | Residue |
O | VAL22 |
O | SER23 |
O | THR75 |
O | ARG78 |