5H4P

Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1

This is a large structure.
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Functional Information from GO Data

ChainGOidnamespacecontents
y0005737cellular_componentcytoplasm
y0005829cellular_componentcytosol
y0005730cellular_componentnucleolus
y0005634cellular_componentnucleus
y0030687cellular_componentpreribosome, large subunit precursor
y0043023molecular_functionribosomal large subunit binding
y0043022molecular_functionribosome binding
y0003743molecular_functiontranslation initiation factor activity
y1902626biological_processassembly of large subunit precursor of preribosome
y0000466biological_processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
y0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
y0042256biological_processmature ribosome assembly
y0042273biological_processribosomal large subunit biogenesis
y0000054biological_processribosomal subunit export from nucleus
y0006364biological_processrRNA processing
w0005737cellular_componentcytoplasm
w0005829cellular_componentcytosol
w0005654cellular_componentnucleoplasm
w0005634cellular_componentnucleus
w0070180molecular_functionlarge ribosomal subunit rRNA binding
w0043023molecular_functionribosomal large subunit binding
w0000055biological_processribosomal large subunit export from nucleus
z0005737cellular_componentcytoplasm
z0022625cellular_componentcytosolic large ribosomal subunit
z0030687cellular_componentpreribosome, large subunit precursor
z0046872molecular_functionmetal ion binding
z0042273biological_processribosomal large subunit biogenesis
J0022625cellular_componentcytosolic large ribosomal subunit
J0005634cellular_componentnucleus
J0019843molecular_functionrRNA binding
J0003735molecular_functionstructural constituent of ribosome
J0002181biological_processcytoplasmic translation
J0000027biological_processribosomal large subunit assembly
L0022625cellular_componentcytosolic large ribosomal subunit
L0003735molecular_functionstructural constituent of ribosome
L0002181biological_processcytoplasmic translation
M0022625cellular_componentcytosolic large ribosomal subunit
M0003723molecular_functionRNA binding
M0003735molecular_functionstructural constituent of ribosome
M0002181biological_processcytoplasmic translation
M0016236biological_processmacroautophagy
M0042273biological_processribosomal large subunit biogenesis
N0022625cellular_componentcytosolic large ribosomal subunit
N0003723molecular_functionRNA binding
N0003735molecular_functionstructural constituent of ribosome
N0002181biological_processcytoplasmic translation
O0022625cellular_componentcytosolic large ribosomal subunit
O0005840cellular_componentribosome
O0003729molecular_functionmRNA binding
O0003723molecular_functionRNA binding
O0003735molecular_functionstructural constituent of ribosome
O0002181biological_processcytoplasmic translation
O0017148biological_processnegative regulation of translation
P0005737cellular_componentcytoplasm
P0022625cellular_componentcytosolic large ribosomal subunit
P0030687cellular_componentpreribosome, large subunit precursor
P0003735molecular_functionstructural constituent of ribosome
P0000448biological_processcleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
P0002181biological_processcytoplasmic translation
Q0022625cellular_componentcytosolic large ribosomal subunit
Q0003735molecular_functionstructural constituent of ribosome
Q0002181biological_processcytoplasmic translation
R0022625cellular_componentcytosolic large ribosomal subunit
R0003723molecular_functionRNA binding
R0003735molecular_functionstructural constituent of ribosome
R0002181biological_processcytoplasmic translation
S0022625cellular_componentcytosolic large ribosomal subunit
S0003735molecular_functionstructural constituent of ribosome
S0002181biological_processcytoplasmic translation
T0022625cellular_componentcytosolic large ribosomal subunit
T0003735molecular_functionstructural constituent of ribosome
T0002181biological_processcytoplasmic translation
U0022625cellular_componentcytosolic large ribosomal subunit
U0003723molecular_functionRNA binding
U0003735molecular_functionstructural constituent of ribosome
U0002181biological_processcytoplasmic translation
V0022625cellular_componentcytosolic large ribosomal subunit
V0070180molecular_functionlarge ribosomal subunit rRNA binding
V0003735molecular_functionstructural constituent of ribosome
V0002181biological_processcytoplasmic translation
W0022625cellular_componentcytosolic large ribosomal subunit
W0003723molecular_functionRNA binding
W0003735molecular_functionstructural constituent of ribosome
W1902626biological_processassembly of large subunit precursor of preribosome
W0002181biological_processcytoplasmic translation
W0000027biological_processribosomal large subunit assembly
W0006412biological_processtranslation
X0022625cellular_componentcytosolic large ribosomal subunit
X0030687cellular_componentpreribosome, large subunit precursor
X0003723molecular_functionRNA binding
X0019843molecular_functionrRNA binding
X0003735molecular_functionstructural constituent of ribosome
X0002181biological_processcytoplasmic translation
X0000027biological_processribosomal large subunit assembly
Y0022625cellular_componentcytosolic large ribosomal subunit
Y0003723molecular_functionRNA binding
Y0003735molecular_functionstructural constituent of ribosome
Y0002181biological_processcytoplasmic translation
Y0042273biological_processribosomal large subunit biogenesis
Z0022625cellular_componentcytosolic large ribosomal subunit
Z0003735molecular_functionstructural constituent of ribosome
Z0002181biological_processcytoplasmic translation
a0022625cellular_componentcytosolic large ribosomal subunit
a0005634cellular_componentnucleus
a0003723molecular_functionRNA binding
a0003735molecular_functionstructural constituent of ribosome
a0002181biological_processcytoplasmic translation
b0005737cellular_componentcytoplasm
b0022625cellular_componentcytosolic large ribosomal subunit
b0003735molecular_functionstructural constituent of ribosome
b0002181biological_processcytoplasmic translation
A0022625cellular_componentcytosolic large ribosomal subunit
A0019843molecular_functionrRNA binding
A0003735molecular_functionstructural constituent of ribosome
A0002181biological_processcytoplasmic translation
c0005737cellular_componentcytoplasm
c0022625cellular_componentcytosolic large ribosomal subunit
c0030627molecular_functionpre-mRNA 5'-splice site binding
c0003723molecular_functionRNA binding
c0003735molecular_functionstructural constituent of ribosome
c0002181biological_processcytoplasmic translation
c0048025biological_processnegative regulation of mRNA splicing, via spliceosome
c0006364biological_processrRNA processing
d0022625cellular_componentcytosolic large ribosomal subunit
d0003735molecular_functionstructural constituent of ribosome
d0002181biological_processcytoplasmic translation
d0006450biological_processregulation of translational fidelity
e0022625cellular_componentcytosolic large ribosomal subunit
e0003735molecular_functionstructural constituent of ribosome
e0002181biological_processcytoplasmic translation
f0022625cellular_componentcytosolic large ribosomal subunit
f0003735molecular_functionstructural constituent of ribosome
f0002181biological_processcytoplasmic translation
f0042273biological_processribosomal large subunit biogenesis
g0022625cellular_componentcytosolic large ribosomal subunit
g0030687cellular_componentpreribosome, large subunit precursor
g0003735molecular_functionstructural constituent of ribosome
g0002181biological_processcytoplasmic translation
g0042254biological_processribosome biogenesis
h0022625cellular_componentcytosolic large ribosomal subunit
h0030687cellular_componentpreribosome, large subunit precursor
h0003729molecular_functionmRNA binding
h0003735molecular_functionstructural constituent of ribosome
h0002181biological_processcytoplasmic translation
h0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
i0022625cellular_componentcytosolic large ribosomal subunit
i0003723molecular_functionRNA binding
i0003735molecular_functionstructural constituent of ribosome
i0002181biological_processcytoplasmic translation
j0022625cellular_componentcytosolic large ribosomal subunit
j0030687cellular_componentpreribosome, large subunit precursor
j0046872molecular_functionmetal ion binding
j0019843molecular_functionrRNA binding
j0003735molecular_functionstructural constituent of ribosome
j0000448biological_processcleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
j0002181biological_processcytoplasmic translation
k0022625cellular_componentcytosolic large ribosomal subunit
k0003735molecular_functionstructural constituent of ribosome
k0002181biological_processcytoplasmic translation
l0022625cellular_componentcytosolic large ribosomal subunit
l0003735molecular_functionstructural constituent of ribosome
l0002181biological_processcytoplasmic translation
B0022625cellular_componentcytosolic large ribosomal subunit
B0003735molecular_functionstructural constituent of ribosome
B0002181biological_processcytoplasmic translation
B1990145biological_processmaintenance of translational fidelity
B0000027biological_processribosomal large subunit assembly
B0006364biological_processrRNA processing
p0022625cellular_componentcytosolic large ribosomal subunit
p0046872molecular_functionmetal ion binding
p0003735molecular_functionstructural constituent of ribosome
p0002181biological_processcytoplasmic translation
o0022625cellular_componentcytosolic large ribosomal subunit
o0003735molecular_functionstructural constituent of ribosome
o0002181biological_processcytoplasmic translation
o0046898biological_processresponse to cycloheximide
C0022625cellular_componentcytosolic large ribosomal subunit
C0005634cellular_componentnucleus
C0003723molecular_functionRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0002181biological_processcytoplasmic translation
D0022625cellular_componentcytosolic large ribosomal subunit
D0005634cellular_componentnucleus
D0008097molecular_function5S rRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0002181biological_processcytoplasmic translation
D0000027biological_processribosomal large subunit assembly
E0022625cellular_componentcytosolic large ribosomal subunit
E0003723molecular_functionRNA binding
E0003735molecular_functionstructural constituent of ribosome
E0002181biological_processcytoplasmic translation
E0000027biological_processribosomal large subunit assembly
F0005737cellular_componentcytoplasm
F0022625cellular_componentcytosolic large ribosomal subunit
F0003735molecular_functionstructural constituent of ribosome
F0002181biological_processcytoplasmic translation
F0000470biological_processmaturation of LSU-rRNA
F0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F0042273biological_processribosomal large subunit biogenesis
G0022625cellular_componentcytosolic large ribosomal subunit
G0003723molecular_functionRNA binding
G0003735molecular_functionstructural constituent of ribosome
G0002181biological_processcytoplasmic translation
G0000470biological_processmaturation of LSU-rRNA
H0022625cellular_componentcytosolic large ribosomal subunit
H0019843molecular_functionrRNA binding
H0003735molecular_functionstructural constituent of ribosome
H0002181biological_processcytoplasmic translation
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI14Zinc. {ECO:0000269|PubMed:22096102}
ChainResidueDetails
jCYS19
jCYS22
jCYS34
jCYS37

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Catalytic Information from CSA

site_idNumber of ResiduesDetails