Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0019082 | biological_process | viral protein processing |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0019082 | biological_process | viral protein processing |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR CHAIN D OF N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~- ((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3- YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE |
| Chain | Residue |
| B | SER1 |
| B | GLN164 |
| B | ILE165 |
| B | GLU166 |
| B | GLY168 |
| B | HIS172 |
| B | PRO189 |
| B | SER190 |
| B | LEU191 |
| B | LYS254 |
| B | MET297 |
| B | THR25 |
| B | HOH444 |
| B | HOH446 |
| B | HOH461 |
| D | HOH101 |
| B | VAL26 |
| B | THR47 |
| B | ILE51 |
| B | PHE139 |
| B | GLY142 |
| B | CYS144 |
| B | HIS163 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR CHAIN E OF N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~- ((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3- YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE |
| Chain | Residue |
| A | VAL26 |
| A | LEU27 |
| A | HIS41 |
| A | PHE139 |
| A | GLY142 |
| A | CYS144 |
| A | HIS163 |
| A | GLN164 |
| A | ILE165 |
| A | GLU166 |
| A | GLY168 |
| A | ASP187 |
| A | PRO189 |
| A | SER190 |
| A | LEU191 |
| A | HOH522 |
| B | LEU-2 |
| B | LEU191 |
| B | GLU194 |
| E | HOH101 |
| E | HOH102 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For 3CL-PRO activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00772","evidenceCode":"ECO:0000255"}]} |
