5GV2

Crystal structure of Arginine-bound CASTOR1 from Homo sapiens

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0034198	biological_process	cellular response to amino acid starvation
A	0034618	molecular_function	arginine binding
A	0042802	molecular_function	identical protein binding
A	0061700	cellular_component	GATOR2 complex
A	0140299	molecular_function	small molecule sensor activity
A	0140311	molecular_function	protein sequestering activity
A	1903577	biological_process	cellular response to L-arginine
A	1904262	biological_process	negative regulation of TORC1 signaling
A	1904263	biological_process	positive regulation of TORC1 signaling
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0034198	biological_process	cellular response to amino acid starvation
C	0034618	molecular_function	arginine binding
C	0042802	molecular_function	identical protein binding
C	0061700	cellular_component	GATOR2 complex
C	0140299	molecular_function	small molecule sensor activity
C	0140311	molecular_function	protein sequestering activity
C	1903577	biological_process	cellular response to L-arginine
C	1904262	biological_process	negative regulation of TORC1 signaling
C	1904263	biological_process	positive regulation of TORC1 signaling

Functional Information from PDB Data

site_id	AC2
Number of Residues	16
Details	binding site for residue ARG A 401

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269\|PubMed:27487210, ECO:0007744\|PDB:5I2C

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine; by PKB/AKT1 => ECO:0000269\|PubMed:33594058