5GTR
estrogen receptor alpha in complex with a stabilized peptide antagonist 6
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue EST A 601 |
| Chain | Residue |
| A | LEU346 |
| A | LEU525 |
| A | ALA350 |
| A | GLU353 |
| A | LEU387 |
| A | MET388 |
| A | LEU391 |
| A | ARG394 |
| A | MET421 |
| A | HIS524 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residues IAS C 2 and DPP C 5 |
| Chain | Residue |
| A | LYS416 |
| A | GLU542 |
| C | ARG1 |
| C | ILE3 |
| C | 0JY4 |
| C | ARG6 |
| C | 0JY7 |
| C | GLN9 |
| C | NH210 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residues 0JY C 4 and DPP C 5 |
| Chain | Residue |
| A | ILE358 |
| A | VAL376 |
| A | GLU542 |
| A | MET543 |
| C | ARG1 |
| C | IAS2 |
| C | ILE3 |
| C | ARG6 |
| C | 0JY7 |
| C | 0JY8 |
| C | GLN9 |
| C | NH210 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residues 0JY C 7 and 0JY C 8 |
| Chain | Residue |
| A | VAL355 |
| A | ILE358 |
| A | LYS362 |
| A | LEU372 |
| A | GLN375 |
| A | LEU379 |
| C | ILE3 |
| C | 0JY4 |
| C | DPP5 |
| C | ARG6 |
| C | GLN9 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9338790","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9600906","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ERE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by Tyr-kinases","evidences":[{"source":"PubMed","id":"7539106","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
