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5GSW

Crystal structure of EV71 3C in complex with N69S 1.8k

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0004197molecular_functioncysteine-type endopeptidase activity
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0008234molecular_functioncysteine-type peptidase activity
A0016787molecular_functionhydrolase activity
A0019028cellular_componentviral capsid
A0019062biological_processvirion attachment to host cell
A0030430cellular_componenthost cell cytoplasm
A0039618cellular_componentT=pseudo3 icosahedral viral capsid
A0044423cellular_componentvirion component
A0046718biological_processsymbiont entry into host cell
B0003723molecular_functionRNA binding
B0004197molecular_functioncysteine-type endopeptidase activity
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0008234molecular_functioncysteine-type peptidase activity
B0016787molecular_functionhydrolase activity
B0019028cellular_componentviral capsid
B0019062biological_processvirion attachment to host cell
B0030430cellular_componenthost cell cytoplasm
B0039618cellular_componentT=pseudo3 icosahedral viral capsid
B0044423cellular_componentvirion component
B0046718biological_processsymbiont entry into host cell
C0003723molecular_functionRNA binding
C0004197molecular_functioncysteine-type endopeptidase activity
C0006508biological_processproteolysis
C0008233molecular_functionpeptidase activity
C0008234molecular_functioncysteine-type peptidase activity
C0016787molecular_functionhydrolase activity
C0019028cellular_componentviral capsid
C0019062biological_processvirion attachment to host cell
C0030430cellular_componenthost cell cytoplasm
C0039618cellular_componentT=pseudo3 icosahedral viral capsid
C0044423cellular_componentvirion component
C0046718biological_processsymbiont entry into host cell
D0003723molecular_functionRNA binding
D0004197molecular_functioncysteine-type endopeptidase activity
D0006508biological_processproteolysis
D0008233molecular_functionpeptidase activity
D0008234molecular_functioncysteine-type peptidase activity
D0016787molecular_functionhydrolase activity
D0019028cellular_componentviral capsid
D0019062biological_processvirion attachment to host cell
D0030430cellular_componenthost cell cytoplasm
D0039618cellular_componentT=pseudo3 icosahedral viral capsid
D0044423cellular_componentvirion component
D0046718biological_processsymbiont entry into host cell
E0003723molecular_functionRNA binding
E0004197molecular_functioncysteine-type endopeptidase activity
E0006508biological_processproteolysis
E0008233molecular_functionpeptidase activity
E0008234molecular_functioncysteine-type peptidase activity
E0016787molecular_functionhydrolase activity
E0019028cellular_componentviral capsid
E0019062biological_processvirion attachment to host cell
E0030430cellular_componenthost cell cytoplasm
E0039618cellular_componentT=pseudo3 icosahedral viral capsid
E0044423cellular_componentvirion component
E0046718biological_processsymbiont entry into host cell
Functional Information from PDB Data
site_idAC1
Number of Residues15
Detailsbinding site for residue 5GI A 201
ChainResidue
APHE25
ACYS147
AHIS161
AILE162
AGLY163
AGLY164
EHIS108
AHIS40
AGLU71
ALEU127
ASER128
ALYS130
ATHR132
ATHR142
ALYS143

site_idAC2
Number of Residues13
Detailsbinding site for residue 5GI B 201
ChainResidue
BHIS40
BGLU71
BLEU127
BLYS130
BTHR132
BTHR142
BLYS143
BALA144
BCYS147
BHIS161
BILE162
BGLY163
BGLY164

site_idAC3
Number of Residues18
Detailsbinding site for residue 5GI C 201
ChainResidue
CARG39
CHIS40
CGLU71
CLEU127
CSER128
CTHR132
CTHR142
CLYS143
CALA144
CCYS147
CHIS161
CILE162
CGLY163
CGLY164
CHOH301
DGLU107
DHIS108
DPRO110

site_idAC4
Number of Residues15
Detailsbinding site for residue 5GI D 201
ChainResidue
DARG39
DHIS40
DGLU71
DLEU127
DSER128
DLYS130
DTHR132
DTHR142
DLYS143
DALA144
DCYS147
DHIS161
DILE162
DGLY163
DGLY164

site_idAC5
Number of Residues11
Detailsbinding site for residue 5GI E 201
ChainResidue
EARG39
EHIS40
EGLU71
ELYS130
ETHR142
ELYS143
ECYS147
EHIS161
EILE162
EGLY163
EGLY164

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PDB entries from 2026-01-14

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