5GOM
Truncated mitofusin-1, transition-like state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005741 | cellular_component | mitochondrial outer membrane |
| A | 0008053 | biological_process | mitochondrial fusion |
| A | 0016020 | cellular_component | membrane |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005741 | cellular_component | mitochondrial outer membrane |
| B | 0008053 | biological_process | mitochondrial fusion |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue GDP A 901 |
| Chain | Residue |
| A | SER85 |
| A | ASN237 |
| A | ARG238 |
| A | ASP240 |
| A | SER284 |
| A | ALA285 |
| A | LYS286 |
| A | SER86 |
| A | GLY87 |
| A | LYS88 |
| A | SER89 |
| A | SER90 |
| A | SER103 |
| A | GLY104 |
| A | HIS107 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue GDP B 901 |
| Chain | Residue |
| B | SER85 |
| B | GLY87 |
| B | LYS88 |
| B | SER89 |
| B | SER90 |
| B | SER103 |
| B | HIS107 |
| B | ASN237 |
| B | ARG238 |
| B | ASP240 |
| B | SER284 |
| B | ALA285 |
| B | LYS286 |
| B | LEU306 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 249 |
| Details | Domain: {"description":"Dynamin-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 180 |
| Details | Region: {"description":"Part of a helix bundle domain, formed by helices from N-terminal and C-terminal regions","evidences":[{"source":"PubMed","id":"16959974","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114303","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Region: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Region: {"description":"G2 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Region: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Region: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Region: {"description":"G5 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27920125","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GNR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GNS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27920125","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GNS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27920125","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GNR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27920125","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GNS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
