5GOF

Truncated mitofusin-1, GTP-bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005741	cellular_component	mitochondrial outer membrane
A	0008053	biological_process	mitochondrial fusion
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue GTP A 901

Chain	Residue
A	THR84
A	ARG238
A	ASP240
A	SER284
A	ALA285
A	LYS286
A	MG902
A	HOH1001
A	HOH1102
A	HOH1106
A	HOH1125
A	SER85
A	HOH1148
A	HOH1224
A	HOH1277
A	SER86
A	GLY87
A	LYS88
A	SER89
A	SER90
A	GLY106
A	ASN237

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 902

Chain	Residue
A	SER89
A	GTP901
A	HOH1102
A	HOH1106
A	HOH1224

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 903

Chain	Residue
A	CYS111
A	HIS144
A	HIS147
A	CYS156

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	90
Details	Region: {"description":"Part of a helix bundle domain, formed by helices from N-terminal and C-terminal regions","evidences":[{"source":"PubMed","id":"16959974","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114303","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Region: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Region: {"description":"G2 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Region: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Region: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Region: {"description":"G5 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27920125","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GNR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GNS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27920125","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GNS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27920125","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GNR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GOF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27920125","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GNS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---