Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5GNM

Cytochrome P450 Vdh (CYP107BR1) L348M mutant

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005506molecular_functioniron ion binding
A0005737cellular_componentcytoplasm
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0020037molecular_functionheme binding
A0046872molecular_functionmetal ion binding
A0047103molecular_functionobsolete 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity
A0047748molecular_functioncholestanetetraol 26-dehydrogenase activity
A0047749molecular_functionobsolete cholestanetriol 26-monooxygenase activity
B0004497molecular_functionmonooxygenase activity
B0005506molecular_functioniron ion binding
B0005737cellular_componentcytoplasm
B0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
B0020037molecular_functionheme binding
B0046872molecular_functionmetal ion binding
B0047103molecular_functionobsolete 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity
B0047748molecular_functioncholestanetetraol 26-dehydrogenase activity
B0047749molecular_functionobsolete cholestanetriol 26-monooxygenase activity
C0004497molecular_functionmonooxygenase activity
C0005506molecular_functioniron ion binding
C0005737cellular_componentcytoplasm
C0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
C0020037molecular_functionheme binding
C0046872molecular_functionmetal ion binding
C0047103molecular_functionobsolete 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity
C0047748molecular_functioncholestanetetraol 26-dehydrogenase activity
C0047749molecular_functionobsolete cholestanetriol 26-monooxygenase activity
D0004497molecular_functionmonooxygenase activity
D0005506molecular_functioniron ion binding
D0005737cellular_componentcytoplasm
D0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
D0020037molecular_functionheme binding
D0046872molecular_functionmetal ion binding
D0047103molecular_functionobsolete 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity
D0047748molecular_functioncholestanetetraol 26-dehydrogenase activity
D0047749molecular_functionobsolete cholestanetriol 26-monooxygenase activity
Functional Information from PDB Data
site_idAC1
Number of Residues22
Detailsbinding site for residue HEM A 501
ChainResidue
APHE58
ATHR241
ALEU244
AVAL283
APRO287
AARG289
APHE339
APHE340
AGLY341
AHIS345
ACYS347
ALYS65
AGLY349
AALA353
AHOH623
AMET87
AHIS95
AARG99
ALEU233
AALA236
AGLY237
ATHR240

site_idAC2
Number of Residues22
Detailsbinding site for residue HEM B 501
ChainResidue
BPHE58
BLYS65
BMET87
BILE88
BHIS95
BARG99
BPHE106
BLEU233
BALA236
BGLY237
BTHR240
BTHR241
BLEU244
BALA286
BPRO287
BARG289
BPHE339
BPHE340
BGLY341
BHIS345
BCYS347
BALA353

site_idAC3
Number of Residues23
Detailsbinding site for residue HEM C 501
ChainResidue
CPHE58
CLYS65
CMET87
CILE88
CHIS95
CARG99
CLEU233
CALA236
CGLY237
CTHR240
CTHR241
CPRO282
CPRO287
CARG289
CPHE339
CPHE340
CGLY341
CILE344
CHIS345
CCYS347
CGLY349
CALA353
CHOH604

site_idAC4
Number of Residues22
Detailsbinding site for residue HEM D 501
ChainResidue
DPHE58
DLYS65
DMET87
DILE88
DHIS95
DARG99
DLEU233
DALA236
DTHR240
DTHR241
DPRO282
DPRO287
DARG289
DPHE339
DPHE340
DGLY341
DILE344
DHIS345
DCYS347
DGLY349
DALA353
DHOH626

Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGIHFCMG
ChainResidueDetails
APHE340-GLY349

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: axial binding residue => ECO:0000250|UniProtKB:P0A512
ChainResidueDetails
ACYS347
BCYS347
CCYS347
DCYS347

222624

PDB entries from 2024-07-17

PDB statisticsPDBj update infoContact PDBjnumon