5GHA
Sulfur Transferase TtuA in complex with Sulfur Carrier TtuB
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0002098 | biological_process | tRNA wobble uridine modification |
| A | 0002143 | biological_process | tRNA wobble position uridine thiolation |
| A | 0002144 | cellular_component | cytosolic tRNA wobble base thiouridylase complex |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008033 | biological_process | tRNA processing |
| A | 0016740 | molecular_function | transferase activity |
| A | 0034227 | biological_process | tRNA thio-modification |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0002098 | biological_process | tRNA wobble uridine modification |
| B | 0002143 | biological_process | tRNA wobble position uridine thiolation |
| B | 0002144 | cellular_component | cytosolic tRNA wobble base thiouridylase complex |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008033 | biological_process | tRNA processing |
| B | 0016740 | molecular_function | transferase activity |
| B | 0034227 | biological_process | tRNA thio-modification |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| C | 0000049 | molecular_function | tRNA binding |
| C | 0002098 | biological_process | tRNA wobble uridine modification |
| C | 0002143 | biological_process | tRNA wobble position uridine thiolation |
| C | 0002144 | cellular_component | cytosolic tRNA wobble base thiouridylase complex |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008033 | biological_process | tRNA processing |
| C | 0016740 | molecular_function | transferase activity |
| C | 0034227 | biological_process | tRNA thio-modification |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| D | 0000049 | molecular_function | tRNA binding |
| D | 0002098 | biological_process | tRNA wobble uridine modification |
| D | 0002143 | biological_process | tRNA wobble position uridine thiolation |
| D | 0002144 | cellular_component | cytosolic tRNA wobble base thiouridylase complex |
| D | 0005524 | molecular_function | ATP binding |
| D | 0008033 | biological_process | tRNA processing |
| D | 0016740 | molecular_function | transferase activity |
| D | 0034227 | biological_process | tRNA thio-modification |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0008033 | biological_process | tRNA processing |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0008033 | biological_process | tRNA processing |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0008033 | biological_process | tRNA processing |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0008033 | biological_process | tRNA processing |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | CYS3 |
| A | CYS6 |
| A | CYS22 |
| A | HIS25 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 402 |
| Chain | Residue |
| A | CYS274 |
| A | CYS277 |
| A | CYS286 |
| A | CYS289 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | THR282 |
| A | CYS286 |
| A | ALA287 |
| A | THR281 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | ARG69 |
| A | ARG298 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 401 |
| Chain | Residue |
| D | CYS3 |
| D | CYS6 |
| D | CYS22 |
| D | HIS25 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 402 |
| Chain | Residue |
| D | CYS274 |
| D | CYS277 |
| D | CYS286 |
| D | CYS289 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 403 |
| Chain | Residue |
| D | SER55 |
| D | GLY57 |
| D | LYS58 |
| D | ASP59 |
| D | SER60 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 404 |
| Chain | Residue |
| D | SER16 |
| D | ARG17 |
| D | LEU159 |
| D | GLU205 |
| D | GLU241 |
| D | GLY246 |
| D | LEU249 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 401 |
| Chain | Residue |
| B | CYS3 |
| B | CYS6 |
| B | CYS22 |
| B | HIS25 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 402 |
| Chain | Residue |
| B | CYS274 |
| B | CYS277 |
| B | CYS286 |
| B | CYS289 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| B | SER16 |
| B | LEU159 |
| B | GLU205 |
| B | GLU241 |
| B | GLY246 |
| B | LEU249 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | VAL165 |
| B | GLY168 |
| B | ASN169 |
| B | ASN172 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 401 |
| Chain | Residue |
| C | CYS3 |
| C | CYS6 |
| C | CYS22 |
| C | HIS25 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 402 |
| Chain | Residue |
| C | CYS274 |
| C | CYS277 |
| C | CYS286 |
| C | CYS289 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 403 |
| Chain | Residue |
| C | THR281 |
| C | THR282 |
| C | CYS286 |
| C | ALA287 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 404 |
| Chain | Residue |
| C | VAL165 |
| C | GLY168 |
| C | ASN169 |
| C | ASN172 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO E 101 |
| Chain | Residue |
| E | PRO32 |
| E | VAL35 |
| E | VAL36 |
| E | ALA37 |
| E | LEU44 |
| E | LEU46 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28439027, ECO:0007744|PDB:5B4E, ECO:0007744|PDB:5B4F, ECO:0007744|PDB:5GHA |
| Chain | Residue | Details |
| A | CYS274 | |
| A | CYS277 | |
| A | CYS286 | |
| A | CYS289 | |
| D | CYS3 | |
| D | CYS6 | |
| D | CYS22 | |
| D | HIS25 | |
| D | CYS274 | |
| D | CYS277 | |
| D | CYS286 | |
| D | CYS289 | |
| B | CYS3 | |
| B | CYS6 | |
| B | CYS22 | |
| B | HIS25 | |
| B | CYS274 | |
| B | CYS277 | |
| B | CYS286 | |
| B | CYS289 | |
| C | CYS3 | |
| C | CYS6 | |
| C | CYS22 | |
| C | HIS25 | |
| C | CYS274 | |
| C | CYS277 | |
| C | CYS286 | |
| C | CYS289 | |
| A | CYS3 | |
| A | CYS6 | |
| A | CYS22 | |
| A | HIS25 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28439027, ECO:0007744|PDB:5B4E |
| Chain | Residue | Details |
| B | ILE79 | |
| B | GLY156 | |
| B | ASP161 | |
| C | ALA53 | |
| C | ASP59 | |
| C | ILE79 | |
| C | GLY156 | |
| C | ASP161 | |
| B | ASP59 | |
| A | ALA53 | |
| A | ASP59 | |
| A | ILE79 | |
| A | GLY156 | |
| A | ASP161 | |
| D | ALA53 | |
| D | ASP59 | |
| D | ILE79 | |
| D | GLY156 | |
| D | ASP161 | |
| B | ALA53 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28439027, ECO:0007744|PDB:5B4E, ECO:0007744|PDB:5B4F |
| Chain | Residue | Details |
| D | CYS133 | |
| D | CYS222 | |
| B | CYS130 | |
| B | CYS133 | |
| B | CYS222 | |
| C | CYS130 | |
| C | CYS133 | |
| C | CYS222 | |
| A | CYS130 | |
| A | CYS133 | |
| A | CYS222 | |
| D | CYS130 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in TtuB) => ECO:0000269|PubMed:22467871 |
| Chain | Residue | Details |
| C | LYS137 | |
| C | LYS226 | |
| C | LYS229 | |
| B | LYS137 | |
| B | LYS226 | |
| B | LYS229 | |
| A | LYS137 | |
| A | LYS226 | |
| A | LYS229 | |
| D | LYS137 | |
| D | LYS226 | |
| D | LYS229 |
