Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 919 A 1475 |
| Chain | Residue |
| A | VAL179 |
| A | TYR242 |
| A | LEU243 |
| A | ASP244 |
| A | HIS284 |
| A | ALA303 |
| A | ASP304 |
| A | PHE305 |
| A | HOH2042 |
| A | HOH2062 |
| A | ALA192 |
| A | LYS194 |
| A | GLU211 |
| A | LEU215 |
| A | LEU218 |
| A | VAL224 |
| A | PHE240 |
| A | GLU241 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 919 B 1475 |
| Chain | Residue |
| A | HOH2022 |
| B | ALA192 |
| B | LYS194 |
| B | THR207 |
| B | GLU211 |
| B | LEU215 |
| B | LEU218 |
| B | VAL224 |
| B | PHE240 |
| B | GLU241 |
| B | TYR242 |
| B | LEU243 |
| B | ASP244 |
| B | ALA303 |
| B | ASP304 |
| B | ARG309 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1476 |
| Chain | Residue |
| A | ALA221 |
| A | ASN222 |
| A | GLN269 |
| A | ARG272 |
| A | GLU299 |
| A | SER461 |
| A | ILE462 |
| A | HOH2122 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1477 |
| Chain | Residue |
| B | GLU438 |
| B | MET441 |
| B | LYS442 |
| B | HIS454 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1477 |
| Chain | Residue |
| A | VAL224 |
| A | THR225 |
| A | GLU241 |
| A | LEU243 |
| A | LYS301 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1478 |
| Chain | Residue |
| B | LEU427 |
| B | GLN428 |
| B | PHE429 |
| B | HOH2108 |
| B | HOH2118 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGTYATVYkGkskltdnl..........VALK |
| Chain | Residue | Details |
| A | LEU171-LYS194 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpqNLLI |
| Chain | Residue | Details |
| A | VAL282-ILE294 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q04735","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q04735","evidenceCode":"ECO:0000250"}]} |
