Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| B | 0000105 | biological_process | L-histidine biosynthetic process |
| B | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY B 1245 |
| Chain | Residue |
| B | ARG98 |
| B | GLN122 |
| B | HIS167 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1245 |
| Chain | Residue |
| A | GLY225 |
| A | ARG226 |
| A | HOH2017 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1246 |
| Chain | Residue |
| B | ILE223 |
| B | GLY225 |
| B | ARG226 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1247 |
| Chain | Residue |
| A | GLU154 |
| A | TYR194 |
| A | GLN196 |
| B | ALA97 |
| B | HOH2004 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1246 |
| Chain | Residue |
| A | VAL69 |
| A | ALA70 |
| A | VAL72 |
| A | HOH2007 |
| B | PRO162 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 1248 |
| Chain | Residue |
| A | PRO162 |
| B | VAL69 |
| B | VAL72 |
| B | HOH2002 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 1247 |
| Chain | Residue |
| A | MET1 |
| A | ILE2 |
| A | ILE239 |
| A | GLN243 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA B 1249 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY A 1248 |
| Chain | Residue |
| A | ALA97 |
| A | ALA123 |
| B | GLU154 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
