Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5G3T

The structure of the L-tryptophan oxidase VioA from Chromobacterium violaceum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0017000	biological_process	antibiotic biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0017000	biological_process	antibiotic biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0017000	biological_process	antibiotic biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0016491	molecular_function	oxidoreductase activity
D	0017000	biological_process	antibiotic biosynthetic process
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	35
Details	BINDING SITE FOR RESIDUE FDA A 419

Chain	Residue
A	VAL10
A	ARG46
A	GLY61
A	ALA62
A	GLY63
A	ARG64
A	TYR206
A	ARG207
A	LEU208
A	ILE241
A	ALA245
A	GLY11
A	LEU267
A	TYR309
A	TRP359
A	ASP389
A	GLY396
A	TRP397
A	MET398
A	MG420
A	HOH2008
A	HOH2029
A	GLY13
A	HOH2039
A	HOH2053
A	HOH2080
A	HOH2242
A	HOH2262
A	HOH2357
A	ILE14
A	SER15
A	ASP38
A	MET39
A	GLN40
A	GLY45

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 420

Chain	Residue
A	GLY11
A	GLY13
A	GLY16
A	ALA240
A	FDA419

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 421

Chain	Residue
A	ALA360
A	HIS361

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 422

Chain	Residue
A	GLU42
A	ALA43
A	GLN189
A	LYS192
A	HOH2040

site_id	AC5
Number of Residues	36
Details	BINDING SITE FOR RESIDUE FDA B 419

Chain	Residue
B	VAL10
B	GLY11
B	GLY13
B	ILE14
B	SER15
B	ASP38
B	MET39
B	GLN40
B	GLY45
B	ARG46
B	GLY61
B	ALA62
B	GLY63
B	ARG64
B	TYR206
B	ARG207
B	LEU208
B	ILE241
B	ALA245
B	LEU267
B	TYR309
B	TRP359
B	ASP389
B	GLY396
B	TRP397
B	MET398
B	MG421
B	TRS424
B	HOH2005
B	HOH2024
B	HOH2031
B	HOH2045
B	HOH2067
B	HOH2215
B	HOH2226
B	HOH2299

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 420

Chain	Residue
B	LYS103
B	ASN107
B	VAL169
B	HOH2129
B	HOH2136

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 421

Chain	Residue
B	GLY11
B	GLY13
B	GLY16
B	ALA240
B	FDA419

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 422

Chain	Residue
B	HIS97

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 423

Chain	Residue
A	HOH2108
B	ALA360
B	HIS361
B	HOH2008

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE TRS B 424

Chain	Residue
B	HIS163
B	LEU267
B	TYR309
B	VAL363
B	GLY396
B	TRP397
B	FDA419
B	ARG64

site_id	BC2
Number of Residues	38
Details	BINDING SITE FOR RESIDUE FDA C 419

Chain	Residue
C	VAL10
C	GLY11
C	GLY13
C	ILE14
C	SER15
C	ASP38
C	MET39
C	GLN40
C	GLY45
C	ARG46
C	GLY61
C	ALA62
C	GLY63
C	ARG64
C	TYR206
C	ARG207
C	LEU208
C	ILE241
C	ALA245
C	LEU267
C	TRP359
C	GLY362
C	ASP389
C	GLY396
C	TRP397
C	MET398
C	TRS426
C	HOH2011
C	HOH2013
C	HOH2051
C	HOH2054
C	HOH2059
C	HOH2073
C	HOH2081
C	HOH2256
C	HOH2258
C	HOH2355
C	HOH2356

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 420

Chain	Residue
C	ARG406
C	ARG410

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 421

Chain	Residue
C	HIS97

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 422

Chain	Residue
C	ALA360
C	HIS361
C	HOH2020

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL C 423

Chain	Residue
C	ASN293
C	SER339
C	HOH2147
C	HOH2283

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL C 424

Chain	Residue
C	GLU42
C	ALA43
C	GLN189
C	LYS192

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 425

Chain	Residue
C	GLN41
C	LEU204
C	GLY205
C	TYR206
C	ASP225
C	ASP226
D	ARG319

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE TRS C 426

Chain	Residue
C	ARG64
C	HIS163
C	TYR309
C	GLY396
C	TRP397
C	FDA419
C	HOH2294
C	HOH2331

site_id	CC1
Number of Residues	38
Details	BINDING SITE FOR RESIDUE FDA D 419

Chain	Residue
D	VAL10
D	GLY11
D	GLY13
D	ILE14
D	SER15
D	ASP38
D	MET39
D	GLN40
D	GLY45
D	ARG46
D	GLY61
D	ALA62
D	GLY63
D	ARG64
D	TYR206
D	ARG207
D	LEU208
D	ALA240
D	ILE241
D	ALA245
D	LEU267
D	TRP359
D	GLY362
D	ASP389
D	GLY396
D	TRP397
D	MET398
D	MG421
D	MG422
D	TRS425
D	HOH2037
D	HOH2039
D	HOH2046
D	HOH2059
D	HOH2067
D	HOH2224
D	HOH2227
D	HOH2343

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 420

Chain	Residue
D	TYR358
D	ALA360
D	HOH2280
D	HOH2345

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 421

Chain	Residue
D	GLY11
D	GLY13
D	GLY16
D	ALA240
D	FDA419

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 422

Chain	Residue
D	GLY13
D	ILE14
D	GLY44
D	FDA419

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL D 423

Chain	Residue
D	GLU42
D	ALA43
D	GLN189
D	LYS192

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 424

Chain	Residue
D	ALA360
D	HIS361
D	HOH2315

site_id	CC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE TRS D 425

Chain	Residue
D	ARG64
D	HIS163
D	TYR309
D	GLY396
D	TRP397
D	FDA419
D	HOH2274
D	HOH2316

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	BINDING: BINDING => ECO:0000269\|PubMed:27466367

Chain	Residue	Details
A	GLY13
A	TYR309
A	MET398
B	GLY13
B	SER15
B	GLY16
B	ASP38
B	ARG46
B	ARG64
B	HIS163
B	LEU208
A	SER15
B	ALA240
B	TYR309
B	MET398
C	GLY13
C	SER15
C	GLY16
C	ASP38
C	ARG46
C	ARG64
C	HIS163
A	GLY16
C	LEU208
C	ALA240
C	TYR309
C	MET398
D	GLY13
D	SER15
D	GLY16
D	ASP38
D	ARG46
D	ARG64
A	ASP38
D	HIS163
D	LEU208
D	ALA240
D	TYR309
D	MET398
A	ARG46
A	ARG64
A	HIS163
A	LEU208
A	ALA240

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)