5FV4

Pig liver esterase 5 (PLE5)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005783	cellular_component	endoplasmic reticulum
A	0005788	cellular_component	endoplasmic reticulum lumen
A	0005811	cellular_component	lipid droplet
A	0016042	biological_process	lipid catabolic process
A	0016787	molecular_function	hydrolase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
A	0106435	molecular_function	carboxylesterase activity
B	0005783	cellular_component	endoplasmic reticulum
B	0005788	cellular_component	endoplasmic reticulum lumen
B	0005811	cellular_component	lipid droplet
B	0016042	biological_process	lipid catabolic process
B	0016787	molecular_function	hydrolase activity
B	0052689	molecular_function	carboxylic ester hydrolase activity
B	0106435	molecular_function	carboxylesterase activity
C	0005783	cellular_component	endoplasmic reticulum
C	0005788	cellular_component	endoplasmic reticulum lumen
C	0005811	cellular_component	lipid droplet
C	0016042	biological_process	lipid catabolic process
C	0016787	molecular_function	hydrolase activity
C	0052689	molecular_function	carboxylic ester hydrolase activity
C	0106435	molecular_function	carboxylesterase activity
D	0005783	cellular_component	endoplasmic reticulum
D	0005788	cellular_component	endoplasmic reticulum lumen
D	0005811	cellular_component	lipid droplet
D	0016042	biological_process	lipid catabolic process
D	0016787	molecular_function	hydrolase activity
D	0052689	molecular_function	carboxylic ester hydrolase activity
D	0106435	molecular_function	carboxylesterase activity
E	0005783	cellular_component	endoplasmic reticulum
E	0005788	cellular_component	endoplasmic reticulum lumen
E	0005811	cellular_component	lipid droplet
E	0016042	biological_process	lipid catabolic process
E	0016787	molecular_function	hydrolase activity
E	0052689	molecular_function	carboxylic ester hydrolase activity
E	0106435	molecular_function	carboxylesterase activity
F	0005783	cellular_component	endoplasmic reticulum
F	0005788	cellular_component	endoplasmic reticulum lumen
F	0005811	cellular_component	lipid droplet
F	0016042	biological_process	lipid catabolic process
F	0016787	molecular_function	hydrolase activity
F	0052689	molecular_function	carboxylic ester hydrolase activity
F	0106435	molecular_function	carboxylesterase activity

Functional Information from PROSITE/UniProt

site_id	PS00122
Number of Residues	16
Details	CARBOXYLESTERASE_B_1 Carboxylesterases type-B serine active site. FGGdpgsVtIfGeSAG

Chain	Residue	Details
A	PHE191-GLY206

---

site_id	PS00941
Number of Residues	11
Details	CARBOXYLESTERASE_B_2 Carboxylesterases type-B signature 2. EDCLYLNIYtP

Chain	Residue	Details
A	GLU97-PRO107

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	6
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU10039","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Active site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P23141","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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