5FPL
Crystal structure of human JARID1B in complex with CCT363901
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 800 |
| Chain | Residue |
| A | CYS692 |
| A | CYS695 |
| A | CYS715 |
| A | HIS718 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 801 |
| Chain | Residue |
| A | HOH2058 |
| A | LEU90 |
| A | ASN91 |
| A | LEU413 |
| A | THR416 |
| A | GLU419 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 802 |
| Chain | Residue |
| A | HIS499 |
| A | GLU501 |
| A | HIS587 |
| A | QAY901 |
| A | HOH2141 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE QAY A 901 |
| Chain | Residue |
| A | TYR425 |
| A | ASP428 |
| A | TYR488 |
| A | PHE496 |
| A | HIS499 |
| A | GLU501 |
| A | LYS517 |
| A | TRP519 |
| A | HIS587 |
| A | MN802 |
| A | HOH2141 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1755 |
| Chain | Residue |
| A | ASP630 |
| A | CYS699 |
| A | PHE700 |
| A | MET701 |
| A | SER702 |
| A | HOH2206 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1756 |
| Chain | Residue |
| A | GLY524 |
| A | HOH2155 |
| A | HOH2279 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS A 1757 |
| Chain | Residue |
| A | ILE500 |
| A | TRP504 |
| A | ARG584 |
| A | HIS617 |
| A | TYR618 |
| A | LEU621 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 52 |
| Details | ZN_FING: C5HC2 => ECO:0000269|PubMed:26741168, ECO:0000269|PubMed:27214403, ECO:0000269|PubMed:28262558 |
| Chain | Residue | Details |
| A | CYS692-MET744 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P29375 |
| Chain | Residue | Details |
| A | TYR425 | |
| A | SER507 | |
| A | ASN509 | |
| A | LYS517 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:26741168, ECO:0000305|PubMed:27214403, ECO:0000305|PubMed:28262558 |
| Chain | Residue | Details |
| A | HIS499 | |
| A | GLU501 | |
| A | HIS587 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS769 |
