Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071557 | biological_process | histone H3-K27 demethylation |
| A | 0071558 | molecular_function | histone H3-tri/di-methyl-lysine-27 demethylase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0071557 | biological_process | histone H3-K27 demethylation |
| B | 0071558 | molecular_function | histone H3-tri/di-methyl-lysine-27 demethylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 3JI A 1 |
| Chain | Residue |
| A | ARG1246 |
| A | ASN1400 |
| A | TRP1410 |
| A | HIS1470 |
| A | HOH2002 |
| A | HOH2003 |
| A | BCN2640 |
| A | BCN2641 |
| A | CO3000 |
| A | GLN1248 |
| A | THR1330 |
| A | TYR1379 |
| A | LYS1381 |
| A | ARG1386 |
| A | THR1387 |
| A | PRO1388 |
| A | HIS1390 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 2000 |
| Chain | Residue |
| A | CYS1575 |
| A | CYS1578 |
| A | CYS1602 |
| A | CYS1605 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MG A 2639 |
| Chain | Residue |
| A | GLU1415 |
| A | GLU1498 |
| A | HOH2247 |
| A | HOH2248 |
| A | HOH2291 |
| A | HOH2295 |
| A | HOH2458 |
| A | HOH2459 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BCN A 2640 |
| Chain | Residue |
| A | YC81 |
| A | ARG1246 |
| A | LEU1433 |
| A | GLY1435 |
| A | HOH2222 |
| A | HOH2268 |
| A | BCN2641 |
| A | MG2642 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BCN A 2641 |
| Chain | Residue |
| A | YC81 |
| A | HIS1390 |
| A | GLN1391 |
| A | ASN1393 |
| A | BCN2640 |
| A | MG2642 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 2642 |
| Chain | Residue |
| A | BCN2640 |
| A | BCN2641 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CO A 3000 |
| Chain | Residue |
| A | YC81 |
| A | HIS1390 |
| A | GLU1392 |
| A | HIS1470 |
| A | HOH2002 |
| A | HOH2003 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 3JI B 1 |
| Chain | Residue |
| B | ARG1246 |
| B | GLN1248 |
| B | SER1270 |
| B | THR1330 |
| B | TYR1379 |
| B | LYS1381 |
| B | ARG1386 |
| B | THR1387 |
| B | PRO1388 |
| B | HIS1390 |
| B | ASN1400 |
| B | TRP1410 |
| B | HIS1470 |
| B | HOH2001 |
| B | HOH2002 |
| B | BCN2640 |
| B | BCN2641 |
| B | CO3000 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 2000 |
| Chain | Residue |
| B | CYS1575 |
| B | CYS1578 |
| B | CYS1602 |
| B | CYS1605 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MG B 2639 |
| Chain | Residue |
| B | GLU1415 |
| B | GLU1498 |
| B | HOH2187 |
| B | HOH2188 |
| B | HOH2232 |
| B | HOH2345 |
| B | HOH2346 |
| B | HOH2347 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BCN B 2640 |
| Chain | Residue |
| B | YC81 |
| B | ARG1246 |
| B | PRO1388 |
| B | THR1434 |
| B | HOH2172 |
| B | BCN2641 |
| B | MG2642 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BCN B 2641 |
| Chain | Residue |
| B | YC81 |
| B | HIS1390 |
| B | ILE1511 |
| B | HOH2172 |
| B | HOH2205 |
| B | BCN2640 |
| B | MG2642 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG B 2642 |
| Chain | Residue |
| B | BCN2640 |
| B | BCN2641 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CO B 3000 |
| Chain | Residue |
| B | GLU1392 |
| B | HIS1470 |
| B | HOH2001 |
| B | HOH2002 |
| B | YC81 |
| B | HIS1390 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | HIS1390 | |
| A | GLU1392 | |
| B | HIS1390 | |
| B | GLU1392 | |
| Chain | Residue | Details |
| A | HIS1470 | |
| B | CYS1605 | |
| A | CYS1575 | |
| A | CYS1578 | |
| A | CYS1602 | |
| A | CYS1605 | |
| B | HIS1470 | |
| B | CYS1575 | |
| B | CYS1578 | |
| B | CYS1602 | |
