5FF0

HydE from T. maritima in complex with S-adenosyl-L-cysteine and methionine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SFS A 401

Chain	Residue
A	CYS63
A	CYS67
A	TYR69
A	CYS70
A	MET408

---

site_id	AC2
Number of Residues	16
Details	binding site for residue CPS A 402

Chain	Residue
A	ARG284
A	MET324
A	LEU330
A	CPS404
A	CPS405
A	HOH514
A	HOH559
A	HOH566
A	HOH608
A	HOH694
A	HOH709
A	HOH724
A	GLN98
A	PHE99
A	GLY277
A	GLU280

---

site_id	AC3
Number of Residues	13
Details	binding site for residue CPS A 403

Chain	Residue
A	LYS37
A	ASP40
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	HOH621
A	HOH627
A	HOH632
A	HOH712
A	HOH741

---

site_id	AC4
Number of Residues	11
Details	binding site for residue CPS A 404

Chain	Residue
A	ARG29
A	LYS315
A	THR317
A	ALA318
A	CPS402
A	CPS410
A	HOH526
A	HOH563
A	HOH699
A	HOH735
A	HOH749

---

site_id	AC5
Number of Residues	14
Details	binding site for residue CPS A 405

Chain	Residue
A	LYS128
A	PRO321
A	MET324
A	LYS325
A	GLU328
A	CPS402
A	HOH512
A	HOH557
A	HOH633
A	HOH652
A	HOH682
A	HOH718
A	HOH756
A	HOH825

---

site_id	AC6
Number of Residues	3
Details	binding site for residue CL A 406

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	AC7
Number of Residues	4
Details	binding site for residue CL A 407

Chain	Residue
A	ARG159
A	MET291
A	5X8409
A	HOH847

---

site_id	AC8
Number of Residues	12
Details	binding site for residue MET A 408

Chain	Residue
A	GLN107
A	SER108
A	SER136
A	GLY138
A	ARG180
A	TYR303
A	SFS401
A	5X8409
A	HOH569
A	HOH579
A	HOH619
A	HOH624

---

site_id	AC9
Number of Residues	19
Details	binding site for residue 5X8 A 409

Chain	Residue
A	TYR69
A	GLN107
A	ARG159
A	GLU161
A	MET199
A	PRO229
A	ILE231
A	THR268
A	THR269
A	ALA270
A	LEU305
A	TYR306
A	CL407
A	MET408
A	HOH534
A	HOH619
A	HOH622
A	HOH768
A	HOH770

---

site_id	AD1
Number of Residues	8
Details	binding site for residue CPS A 410

Chain	Residue
A	GLU150
A	THR247
A	CPS404
A	HOH668
A	HOH743
A	HOH771
A	ARG29
A	GLU33

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0000269|PubMed:18400755, ECO:0000269|PubMed:19706452, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX

Chain	Residue	Details
A	CYS63

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX

Chain	Residue	Details
A	CYS67
A	CYS70

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIZ, ECO:0007744|PDB:4JXC, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE

Chain	Residue	Details
A	SER311

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE

Chain	Residue	Details
A	SER319
A	SER322

---